Cryosurgery as a Minimally Invasive Alternative Treatment for a Patient with Erosive Adenomatosis of the Nipple

Bae, Kyung‐Nam; Shin, Kihyuk; Kim, Woo-Il; Yang, Min‐Young; Lee, Won‐Ku; Kim, Hoon‐Soo; Ko, Hyun‐Chang; Kim, Byung Soo; Kim, Moon‐Bum; Kim, Gun‐Wook

doi:10.5021/ad.2021.33.2.182

Cited by 6 publications

(5 citation statements)

References 12 publications

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“…7 Additionally, two separate case reports explored cryosurgery, both demonstrating no adverse effects. 11,12 Despite the aesthetic advantages of these approaches, minimizing damage to surrounding healthy tissue, they do not guarantee clean, uninvolved margins. Moreover, the risk of recurrence is not refuted from such a small cohort.…”

Section: Discussionmentioning

confidence: 99%

Nipple Adenoma: Systematic Review of Literature

Berger,

Gersh,

Talisman

2024

Plastic and Reconstructive Surgery - Global Open

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Background: Nipple adenomas (NAs) are rare benign proliferative tumors presenting as palpable nodules, erosive lesions, or nipple discharge, mimicking other conditions. This systematic review categorizes cases into sole NA (ONA) or co-diagnoses with other conditions (CONA) to enhance clinical recognition, diagnosis, and treatment efficacy. Methods: Following PRISMA guidelines, a PubMed search was conducted for NA. Inclusion criteria covered original research, excluding reviews or other breast diseases. Bias risk was assessed through a thorough search, authors independently evaluated studies, and data were synthesized using varied measures. Subgroups ONA and CONA were formed. Analyses were conducted in Excel and R, complemented by a qualitative review due to case report predominance. Biases in case reports were transparently addressed. Results: Of the 86 studies, 387 cases were analyzed, showing 10.34% with co-diagnoses of malignant or premalignant conditions. Mean age was 44, with a female predominance (97%). ONA (347 cases) and CONA (40 cases) subgroups exhibited variations in symptoms, physical findings, and imaging. Treatment modalities included excision (51.39%), biopsy alone (11.1%), and mastectomy (8.6%). Mean follow-up of 56.73 months revealed recurrence (2.87%) and malignancy development (1.79%), notably in CONA cases (33.33%). Conclusions: This study provides insights into the broader age range of NA and its associations. Higher co-diagnosis rates were correlated with older age, highlighting the necessity for thorough investigation, with excision as the primary treatment. Follow-up emphasizes the significance of identifying and monitoring CONA cases, which pose a higher malignancy risk. Recurrence is presumed to be linked to proper lesion excision and co-diagnosis.

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Section: Discussionmentioning

confidence: 99%

Nipple Adenoma: Systematic Review of Literature

Berger,

Gersh,

Talisman

2024

Plastic and Reconstructive Surgery - Global Open

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“… 4 Other authors have reported favorable treatment outcomes with cryosurgery and photodynamic therapy. 5 , 6 …”

Section: Discussionmentioning

confidence: 99%

Case for diagnosis. Unilateral nodule on the nipple: erosive adenomatosis of the nipple

Mendez-Flores

Uriarte-Ruíz

Memija

et al. 2023

Anais Brasileiros de Dermatologia

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“…Lee et al [15] utilized Moh's Micrographic Surgery (MMS) and proposed that, if applied early, it could facilitate the excision of the tumor with the preservation of the nipple. Similarly, Bae et al [16] performed cryosurgery in their patient, a technique that is gaining ground as a minimally invasive treatment of NA as well, with remarkable outcomes as far as aesthetics are concerned.…”

Section: Discussionmentioning

confidence: 99%