Cryoprotectants for red blood cells: Evaluate safety and effectiveness by in vitro measures
Yuying Hu,
Xiangjian Liu,
AKhlaq Ahmad
et al.
Abstract:The transfusion of red blood cells (RBCs) is crucial in current medicinal research. The shelf‐life of donated RBCs preserved by the normal method is very short, limiting their clinical application. Cryopreservation is a reliable and effective technology for the long‐term storage of RBCs. During the process, ice formation will cause irreversible injuries to RBCs. Glycerol is used as a cryoprotectant (CPA) for RBCs to mitigate cryoinjuries. But it severely induces RBC hemolysis and deformation. This review intro… Show more
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