Cryogenic Equipment in Minimally Invasive Surgery

Chizh, N. A.

doi:10.15407/cryo28.03.200

Cited by 2 publications

(3 citation statements)

References 2 publications

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“…Inspection and other utility instruments Automatic sample adding instrument, sample processing system, medical cryogenic equipment, medical refrigeration equipment, medical freezing equipment, etc. [74].…”

Section: Sample Separation Instrumentsmentioning

confidence: 99%

Methods and Advances in the Design, Testing and Development of In Vitro Diagnostic Instruments

Wang

et al. 2023

Processes

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With the continuous improvement of medical testing and instrumentation engineering technologies, the design, testing and development methods of in vitro diagnostic instruments are developing rapidly. In vitro diagnostic instruments are also gradually developing into a class of typical high-end medical equipment. The design of in vitro diagnostic instruments involves a variety of medical diagnostic methods and biochemical, physical and other related technologies, and its development process involves complex system engineering. This paper systematically organizes and summarizes the design, testing and development methods of in vitro diagnostic instruments and their development in recent years, focusing on summarizing the related technologies and core aspects of the R&D process, and analyzes the development trend of the in vitro diagnostic instrument market.

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Section: Sample Separation Instrumentsmentioning

confidence: 99%

Methods and Advances in the Design, Testing and Development of In Vitro Diagnostic Instruments

Wang

et al. 2023

Processes

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“…Ступінь пошкодження клітин залежить від температурно-часових режимів. Отже, найважливішими параметрами кріодеструкції пухлини є рівень низьких температур, експозиція кріовтручання, швидкість заморожування та відтавання тканин, кількість циклів заморожування-відтавання [3,5,11].…”

Section: огляд літературиunclassified

“…The degree of cell damage depends on temperature and time modes. Thus, the most crucial parameters of cryodes-truction of the tumor are low temperatures level, exposure to cryotherapy, the rate of freezing and thawing of tissues, and the number of freezing-thawing cycles [3,5,11].…”

Section: огляд літературиmentioning

confidence: 99%

Cryosurgery and physical medicine n treatment of cancer

2021

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Background. At the present stage of oncology development, cryosurgery is keeping up with other surgical options of treating malignant tumors. However, especially when using cryoapplication technique, radical low-temperature destruction of large tumors is challenged with uneven freezing of the tissue inside and on the periphery of the cryoablation zone resulting in insufficient complete destruction of all tumor cells. The long-term strategy of increasing the efficiency of cryogenic treatment, which will maximize the potential for exposure of biological tissues to low temperatures, is its combination with other physical methods. On the other hand, the preliminary cryotherapy of the tumor tissue can be used to increase the efficiency of antitumor therapy by other methods, in particular, physical ones. Purpose – to summarize and analyze the literature data on applying low temperatures in combination with other physical medicine techniques in order to assess the efficiency and the potential of those in uptodate oncology. Materials and Methods. The paper deals with analyzing the studies published within the period from 2000 to 2020 outlining the data on the impact of low temperatures on the biological tissues in combination with other physical medicine techniques. After keyword search against international and Ukrainian databases, the papers, focused on this subject area, were sorted out, analyzed and included in the references. Results. The review presents pros and cons of using cryosurgery in medical practice with due regard for pathogenetic mechanisms of low temperature impact on biological structures. Based on experimental and clinical studies data, a positive effect of cryosurgical approaches in combination with other physical medicine techniques when performing surgical interventions for ablation of malignant neoplasms has been shown. The paper included the contributions describing the findings on combining cryosurgery with: preliminary hemodilution; radiofrequency and microwave hyperthermic ablation; laser and photodynamic therapy; electroporation. Additionally, a contemporary view of cryo-ultrasound therapy, cryonanoablation, cryo- radiation treatment and cryoelectrolysis was presented. Conclusions. Cryosurgery is an effective minimally invasive surgical method keeping up with other methods of treating malignant tumors, despite the fact that these days the research on optimizing the method of exposure of biological tissues to low temperatures is still ongoing. Cryosurgery in combination with other physical medicine techniques in case of tumor ablation can enhance the effectiveness of treating cancer patients.

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Cryogenic Equipment in Minimally Invasive Surgery

Cited by 2 publications

References 2 publications

Methods and Advances in the Design, Testing and Development of In Vitro Diagnostic Instruments

Methods and Advances in the Design, Testing and Development of In Vitro Diagnostic Instruments

Cryosurgery and physical medicine n treatment of cancer

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