Cryogels and Monoliths: Promising Tools for Chromatographic Purification of Nucleic Acids
João Ribeiro,
Marco Â. Luís,
Bruno Rodrigues
et al.
Abstract:The increasing demand for highly pure biopharmaceuticals has put significant pressure on the biotechnological industry to innovate in production and purification processes. Nucleic acid purification, crucial for gene therapy and vaccine production, presents challenges due to the unique physical and chemical properties of these molecules. Meeting regulatory standards necessitates large quantities of biotherapeutic agents of high purity. While conventional chromatography offers versatility and efficiency, it suf… Show more
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