Cryoballoon ablation for refractory ventricular tachycardia

Cook, Christopher; Welter-Frost, Allan; Wilson, David R.; Herweg, Bengt

doi:10.1016/j.hrcr.2022.12.012

Cited by 2 publications

(1 citation statement)

References 4 publications

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“…Laser energy continues to be investigated at the pre-clinical level for ventricular rhythm applications [ 69 ]; nonetheless, its use remains focused on lead extractions due to operator familiarity with radiofrequency energy. Similarly, cryoballoons have been utilized for ventricular substrates at the case series level [ 70 ] but are rarely used for monomorphic ventricular tachycardia, and thus, no success rates nor complication rates can be confidently assessed.…”

Section: Pulsed-field Ablation For Arrhythmogenic Substrate Suppressionmentioning

confidence: 99%

Opportunities and Challenges in Catheter-Based Irreversible Electroporation for Ventricular Tachycardia

Repp,

Chinyere

2024

Pathophysiology

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The use of catheter-based irreversible electroporation in clinical cardiac laboratories, termed pulsed-field ablation (PFA), is gaining international momentum among cardiac electrophysiology proceduralists for the non-thermal management of both atrial and ventricular tachyrhythmogenic substrates. One area of potential application for PFA is in the mitigation of ventricular tachycardia (VT) risk in the setting of ischemia-mediated myocardial fibrosis, as evidenced by recently published clinical case reports. The efficacy of tissue electroporation has been documented in other branches of science and medicine; however, ventricular PFA’s potential advantages and pitfalls are less understood. This comprehensive review will briefly summarize the pathophysiological mechanisms underlying VT and then summarize the pre-clinical and adult clinical data published to date on PFA’s effectiveness in treating monomorphic VT. These data will be contrasted with the effectiveness ascribed to thermal cardiac ablation modalities to treat VT, namely radiofrequency energy and liquid nitrogen-based cryoablation.

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Section: Pulsed-field Ablation For Arrhythmogenic Substrate Suppressionmentioning

confidence: 99%