Cryoablation treatment of benign breast lesions with 12-month follow-up

Kaufman, Cary S.; Bachman, Barbara; Littrup, Peter J.; Freeman-Gibb, Laurie; White, Michael; Carolin, Kathryn A; Francescatti, Darius; Stocks, Lewis H.; Smith, J. Stanley; Henry, Caitlin; Bailey, Lisa; Harness, Jay K.; Simmons, Rache M.

doi:10.1016/j.amjsurg.2004.06.025

Cited by 44 publications

(49 citation statements)

References 25 publications

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“…In 2002, Kaufman et al (11) reported to use a table-top (8) again reported the results of a prospective nonrandomized trial of percutaneous cryoablation for 78 benign breast lesions in 63 patients. Eighty-five percent of lesions were fibroadenomas.…”

Section: Clinical Resultsmentioning

confidence: 99%

“…Compared with the above techniques, ultrasound-guided cryoablation of fibroadenomas has been shown to be a costeffective alternative with a low morbidity risk (7)(8)(9)15,19). A number of potential advantages include: v Cryoablation for tumor destruction is well suited for ultrasound guidance and monitoring because the hyperechoic effect obtained with ice-ball formation can be easily identified and therapy can be directed with precision; v This technique is a mini-invasive and virtually painless procedure, can be performed under local anesthesia in an office-based breast clinic; v There is an excellent cosmesis without tissue removal and minimal scarring.…”

Section: Discussionmentioning

confidence: 99%

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Cryosurgery for Breast Fibroadenomas

Niu¹,

Wu²,

Xu³

2012

Modern Cryosurgery for Cancer

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Fibroadenomas are the most common benign tumors in the breast of women during their second and third decades of life, and account for 30% and 50% of all breast biopsies, and these rates rise to about 75% for biopsies in women under the age of 20. The tumors commonly present a painless, palpable, solid, rubbery, well-circumscribed, and movable mass with no associated risk of carcinoma. With the vast array of image-guided biopsy devices, fibroadenomas can be easily sampled and diagnosed. With use of ultrasoundguided cryoablation for breast fibroadenomas, there is little or no pain, targeted lesions are reduced in size or eliminated, scarring is minimal, cosmesis is outstanding, and patient satisfaction is excellent. Cryosurgery should be a preferred option for those patients desiring definitive therapy for their fibroadenomas without surgical intervention.

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Section: Clinical Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Cryosurgery for Breast Fibroadenomas

Niu¹,

Wu²,

Xu³

2012

Modern Cryosurgery for Cancer

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“…Several investigators reported that cryotherapy ablation can successfully be applied as a treatment option for benign tumors such as fibroadenomas [55,56]. Currently, the U.S. Food and Drug Administration has approved cryotherapy without resection as a treatment option for core biopsyproven fibroadenomas.…”

Section: Cryotherapymentioning

confidence: 99%

Minimally Invasive Approaches for Diagnosis and Treatment of Early-Stage Breast Cancer

Vlastos

Verkooijen

2007

The Oncologist

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LEARNING OBJECTIVESAfter completing this course, the reader will be able to:1. Describe the minimally invasive approaches to breast cancer diagnosis and treatment.2. List the strengths and weaknesses of minimally invasive diagnostic and treatment procedures.3. Select appropriate patients for minimally invasive approaches to breast cancer diagnosis and treatment.Access and take the CME test online and receive 1 AMA PRA Category 1 Credit ™ at CME.TheOncologist.com CME CME ABSTRACTBreast cancer management has been evolving toward minimally invasive approaches. Image-guided percutaneous biopsy techniques provide accurate histologic diagnosis without the need for surgical biopsy. Breast conservation therapy has become the treatment standard for earlystage breast cancer. Sentinel lymph node biopsy is a new procedure that can predict axillary lymph node status without the need of axillary lymph node dissection. The next challenge is to treat primary tumors without surgery. For this purpose, several new minimally invasive procedures, including radiofrequency ablation, interstitial laser ablation, focused ultrasound ablation, and cryotherapy, are currently under development and may offer effective tumor management and provide treatment options that are psychologically and cosmetically more acceptable to the patients than are traditional surgical therapies. In this review, we give an overview of minimally invasive approaches for the diagnostic and therapeutic management of early-stage breast cancer. The Oncologist 2007;12: [1][2][3][4][5][6][7][8][9][10]

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“…9 Others have shown that cryoablation is highly successful in treating fibroadenomas and other benign breast lesions. [10][11][12][13][14][15] In 2001, the Visica™ system for cryoablation of fibroadenomas was approved by the US Food and Drug Administration (FDA). 16,17 Cryoassisted lumpectomy is another application of this technique for the localization and removal of non-palpable breast lesions.…”

Section: R Y O a B L A T I O N To D A Ymentioning

confidence: 99%

“…37 Overall, the scarring is considered minimal, the recovery is fast, and patient's self-image is preserved with a high rate of patient satisfaction. 12,14 Due to the fact that the only invasive maneuver is the insertion of the cryoprobe through a 3mm incision in the breast under aseptic technique, the risk of infection is minimal, and there are low rates of treatment-related complications. An important aspect of cryotherapy is that the treatment can be repeated as many times as needed for either recurrences or new lesions, particularly for treating benign lesions.…”

Section: T H E a D V A N T A G E S A N D D I S A D V A N T A G E S O mentioning

confidence: 99%