Cryoablation for recurrent renal tumors after primary nephron-sparing surgery using an innovative liquid nitrogen-based cryogenic device

Percutaneous treatment of renal tumours

“…In the literature, there are also liquid nitrogen-based systems. 25 Tissue destruction occurs by freezing, causing crystallization of cytoplasmic fluid, and thawing which melts the crystallized fluid resulting in rupture of cell membranes and cellular dehydration. 26,27 Cryoablation causes microvascular thrombosis that can also lead to cell death.…”

“…Current cryoablation tools are argon‐based systems that use the Joules‐Thompson principle to create an ice‐ball. In the literature, there are also liquid nitrogen‐based systems 25 . Tissue destruction occurs by freezing, causing crystallization of cytoplasmic fluid, and thawing which melts the crystallized fluid resulting in rupture of cell membranes and cellular dehydration 26,27 .…”