Cry analysis in infants with Rh haemolytic disease

Abstract

Cry analysis in infants with Rh haemolytic disease. Acta Paediatr Scand 1987; Suppl. 335: 1-73. The influence of hyperbilirubinaemia on the infants' cries and the feasibility of the use of cry analysis for the early identification of developing kernicterus were studied by analyzing the cries of 100 healthy one-day-old infants and 31 infants with Rh haemolytic disease of the newborn (Rh-HDN) by using sound spectrographic methods. The newborn infants with Rh-HDN were divided into three subgroups according to the findings in a neurological examination: an evident group (10 infants), a transient group (13 infants) and an asymptomatic group (8 infants) and followed up until one year of age.Cry recording and a neurological examination were carried out once for each of the healthy one-day-old infants and twice a day during the first week of life for the infants with Rh-HDN, and thereafter once a day until discharged and at the ages of I and 3 months. Additional neurological examinations were performed on the Rh-HDN infants at the ages of 6 and 12 months. Bilirubin determination was carried out in connection with the cry recordings during the first week of life. The effect of blood exchange transfusion on the cry sound was investigated in infants with a bilirubin level above 250 Jlmol/l (n = 12) and below this level (n = IS) before

Interrelations among the acoustic features of cries: How many features do we need?

“…Lynip (1951) published the first study using the sound spectrograph to examine infants' cries, although no quantitative measures were reported. Systematic investigations, begun by a team of Scandinavian researchers, related acoustic features of cries to a variety of neonatal health problems (see reviews by Michelsson & Wasz-Hockert, 1980;Wasz-Hockert, Lind, Vuorenkoski, Partanen & Valanne, 1968;Wasz-Hockert, Michelsson & Lind, 1985) and has resulted in a codified system for acoustic analysis (for example, Koivisto, 1987). The goal of using cry analysis to diagnose infant dysfunction and to predict poor developmental outcomes continues with computerized analysis systems (see Golub & Corwin, 1985;Lester, 1987).…”

“…Even within a single expiration, however, there are many features to measure: spectrographic analyses by the Scandinavian investigators encompass upwards of 20 measures (e.g., Koivisto, 1987;Michelsson, 1980;Wasz-Hockert et al, 1985). Golub (1980) and Golub and Corwin (1985) used some 90 measures.…”

Multimodal Signals: Cognitive and Algorithmic Issues

“…Related to the qualitative aspects analysis, Koivisto (1987) [12] mentions that in healthy infants, as the age increases presentation frequency of some qualitative characteristics of crying diminishes, vibratos in particular. Nonetheless, in our study there is no evidence of this trend, because even in the glottal plosives we can notice an increment.…”

Effects of Hyperbilirubinemia on Cerebrocortical Electrical Activity in Newborns

“…Rough digital EEG data were transformed into power spectral analysis by software, which was written by Medelec Corporation. Analyzed results were given in four different frequency bands [delta (), 0 -4 Hz; theta (␦), 4 -8 Hz; alpha (␣), 8 -13 Hz; and beta (␤), [13][14][15][16][17][18][19][20][21][22] Hz] as percentages of each frequency band. We collected these data in five different regions for every patient (Fp 1 -C 3 , C 3 -O 1 , Fp 2 -C 4 , C 4 -O 2 , and Cz-C 4 ), and it was compared with control group values.…”