Crusted impetigo‐like lesion on the face: a case of IgG/IgA pemphigus

Moriuchi, Reine; Ito, Takanori; Kikuchi, Kazuhiro; Nakashita, N.; Muramatsu, Ryuichi; Natsuga, Ken; Shimizu, Hiroshi; Shimizu, Satoko

doi:10.1111/jdv.14060

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Igg/iga Pemphigus1

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2018

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“…Typical IgG/IgA pemphigus is relatively rare, and only 20 cases have been reported so far. The clinical manifestations in these cases are diverse and characterized by pustules or annular blisters [ 7 ]. In our own clinic, we encountered a case of pustular pemphigus with IgG and IgA antibodies detected by DIF and ELISA, and the titer of Dsg1 IgA was related to the disease activity ( Figure 1 ) [ 8 ].…”

Section: Igg/iga Pemphigusmentioning

confidence: 99%

Antigen recognition in the pathogenesis of immunoglobulin A-related autoimmune bullous diseases

Li¹,

Jing²,

Li³

et al. 2018

pdia

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Immunoglobulin A (IgA) is the most common subtype of antibodies in mucosal surfaces. In most of autoimmune bullous diseases, however, immunoglobulin G (IgG) is the main pathogenic antibody that plays a role through complementation. The IgA antibody for epidermal connection protein can be found in the sera of some patients with blistering skin disease. Of these patients, some have the IgA antibody in their sera, while others have IgG and IgA antibodies. IgA-related autoimmune bullous diseases are less common in clinical practice. In the past, these diseases were not fully understood and their classifications were confusing. Recently, some progress has been made in the study of these diseases.

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Section: Igg/iga Pemphigusmentioning

confidence: 99%