Handbook on Hyperbaric Medicine
DOI: 10.1007/1-4020-4448-8_17
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Crush Injury and Other Acute Traumatic Ischemia

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Cited by 7 publications
(9 citation statements)
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“…HBO therapy as an adjunct should be administered as early as possible to minimize the frequency and extent of tissue necrosis, reduce edema, control infection, support healing and prevent reperfusion injury. [9] A recent retrospective analysis of 70 consecutive sural flaps reported a complication rate of 59% (41 of 70 flaps), with complete necrosis in 19% flaps and partial necrosis in 17%. [10] In a series of lateral supramalleolar flaps by Ehab et al, [6] a total of 5 patients (20%) suffered complications out of 25 patients.…”
Section: Discussionmentioning
confidence: 99%
“…HBO therapy as an adjunct should be administered as early as possible to minimize the frequency and extent of tissue necrosis, reduce edema, control infection, support healing and prevent reperfusion injury. [9] A recent retrospective analysis of 70 consecutive sural flaps reported a complication rate of 59% (41 of 70 flaps), with complete necrosis in 19% flaps and partial necrosis in 17%. [10] In a series of lateral supramalleolar flaps by Ehab et al, [6] a total of 5 patients (20%) suffered complications out of 25 patients.…”
Section: Discussionmentioning
confidence: 99%
“…Adjuvant HBO can be given early to prevent large regions of ischemic necrosis, minimize the frequency and extent of tissue necrosis, reduce edema, control infection, support healing, and prevent reperfusion injury. [9] At the authors' institution, a strategy has been developed to overcome these difficulties and to successfully manage these patients with a combined approach that maximizes tissue perfusion and oxygenation, allowing for surgical correction of such injuries. The current treatment algorithm [ Figure 6] begins with surgical debridement and initiation of HBO therapy in the immediate postoperative period.…”
Section: Discussionmentioning
confidence: 99%
“…[1,3] Traumatic wounds: Crush injury, compartment syndrome Hyperbaric oxygen ameliorates the effects of acute traumatic ischaemia through four mechanisms: hyperoxygenation, vasoconstriction, and influence on reperfusion and host factors. [18] HBOT also decreases neutrophil activation, preventing margination, rolling and Figure 1: Flow chart for patient selection and predictor of outcomes in patients managed with HBOT based on transcutaneous oximetry measurements [15,16] accumulation of WBCs, thereby reducing the production of free radicals by neutrophils and preventing reperfusion injury. [3] HBOT is also seen to reduce sludging of RBCs.…”
Section: Non-healing Wounds: Diabetic Vascular Insuffi Ciency Ulcersmentioning
confidence: 99%
“…Adjuvant HBOT should be administered as soon as possible; when it is given early it can prevent large expanses of ischaemic necrosis, minimise the frequency and extent of amputations, reduce oedema, control infection, support healing and prevent reperfusion injury. [18] Gustilo classification of open fractures is commonly used for objective assessment in crush injuries to determine whether HBOT is indicated or not. For the uncompromised host, HBOT is recommended for all Gustilo Grade III B and III C fractures.…”
Section: Non-healing Wounds: Diabetic Vascular Insuffi Ciency Ulcersmentioning
confidence: 99%
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