CRP in cerebrovascular stroke: Prognostic implications

Shoaeb, M. A.; Shehata, Mohamed; Taema, Khaled; Hammouda, M.

doi:10.1016/j.ejccm.2014.03.001

Cited by 15 publications

(17 citation statements)

References 41 publications

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“…14 In an Egyptian study by Shoaeb et al on 50 patients with a first-ever acute stroke admitted within 24 h of onset reported that serum CRP level on admission was predictive of stroke severity (r = 0.54, P = 0.006) as well as outcome (r = 0.56, P= 0.004). 15 Similar to Shoaeb et al in present study CRP was significantly high in patients with stroke compared to normal. Di Napoli et al studied, the rise of CRP in 72% of patients (P<0.0001) and suggested the CRP as an independent marker of underlying chronic inflammatory process in atherosclerosis.…”

Section: Discussionsupporting

confidence: 80%

A Prospective Study of Evaluation of C - Reactive Protein in Patients of Ischemic Stroke

Majhi¹,

Trikha²,

Udeniya³

et al. 2018

IJCMR

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Section: Discussionsupporting

confidence: 80%

A Prospective Study of Evaluation of C - Reactive Protein in Patients of Ischemic Stroke

Majhi¹,

Trikha²,

Udeniya³

et al. 2018

IJCMR

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“…16 so studies with late measurement of hs-CRP have high levels of hs-CRP compared with earlier studies. This findings are comparable with Shoaeb et al, 12 Mishra et al, 11 whereas high levels in Roudbary et al 17 may be explained by older age of study population and relatively small study population.…”

Section: Mean Hs-crp Levels and Outcome And Mortalitysupporting

confidence: 81%

A STUDY OF HIGH SENSITIVITY C-REACTIVE PROTEIN (hs-CRP) LEVELS IN CEREBROVASCULAR ACCIDENT (STROKE)

Bhaskar¹,

Rao²,

Rajender³

2016

jemds

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World Health Organization (WHO) defined stroke as "rapidly developing clinical signs of focal or global disturbance of cerebral function, lasting more than 24 hours or leading to death with no apparent cause other than vascular origin." OBJECTIVESThe purpose of this study was to determine the frequency of raised hs-CRP levels in patients with first-ever acute ischaemic and haemorrhagic stroke. To evaluate the ability of hs-CRP levels as a biomarker to differentiate between haemorrhagic and ischaemic stroke. To evaluate whether hs-CRP levels in stroke correlate with other risk factors. BACKGROUND AND OBJECTIVECerebrovascular accident, which has considerable mortality and morbidity deserves attention towards its prevention. The first line of defence in stroke prevention are detecting and adequately treating manageable risk factors.

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“…13 Another previous research conducted by Ghabaee et al 12 in 2013 on the use of hs-CRP in predicting the mortality and poor outcomes at an acute ischemic stroke found a sensitivity of 81% and a specificity of 80%. 12 Similarly, a previous research conducted by Shoaeb et al 14 in 2014 on the use of hs-CRP in predicting poor outcomes (with mRS assessment) found a sensitivity of 75% and a specificity of 82%. Unfortunately, there still have not been any researches comparing the accuracy of NLR and hs-CRP values in predicting outcomes of acute ischemic stroke patients.…”

Section: Resultsmentioning

confidence: 85%

Neutrophil-Lymphocyte Ratio and High Sensitivity C-Reactive Protein as Ischemic Stroke Outcome Predictor

Putri¹,

Ganie²,

Rambe³

2018

Indonesian J. Clin. Pathol. Med. Lab.

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Proses inflamasi merupakan perjalanan penyakit dari strok iskemik akut, yang melibatkan penumpukan mediator inflamasi daninfiltrasi leukosit. Nilai Rasio Neutrofil-Limfosit (RNL) di beberapa penelitian dapat digunakan untuk meramalkan strok akibat iskemikakut yang caranya mudah dilakukan. High sensitivity C Reactive Protein (hs-CRP) merupakan reaktan tahap akut yang kadarnyameningkat di strok iskemik. Oleh karena itu bermanfaat sebagai petanda peramal hal terkait. Penelitian ini bertujuan untuk mengetahuiperbedaan nilai antara RNL dan hs-CRP dalam meramalkan hasilan pasien strok iskemik akut. Metode penelitian analitik observasionaldengan rancangan kohort prospektif. Hasil dinilai dengan modified Rankin Scale (mRS) (1–2=baik; 3–6=buruk) dan Barthel Index (BI)(0–20=ketergantungan jumlah keseluruhan, 21-60=berat; 1–90=sedang; 91–99=ringan dan 100=normal). Dari 43 sampel, didapatkanlaki-laki 24 orang (55,8%) dan perempuan 19 orang (44,2%) dengan rerata usia 57,12 ± 9,8 tahun. hubungan positif didapatkansedang dan bermakna antara RNL dengan hasilan mRS dan BI pasien strok iskemik akut (r=0,585; p=0,001 dan r=0,564; p=0,001).Hubungan positif didapatkan kuat dan bermakna antara hs-CRP dan hasilan mRS (r=0,614; p=0,001) serta didapatkan hubunganpositif dengan kekuatan sangat kuat dan bermakna antara hs-CRP dan hasilan n BI pasien strok iskemik akut (r=0,881; p=0,001).Dengan membandingkan ketepatan kedua data didapatkan RNL 86% dan hs-CRP 88% (p=0,6554). Perbedaan tidak bermakna terdapatantara nilai RNL dan hs-CRP sebagai peramal hasilan pasien strok iskemik akut.

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CRP in cerebrovascular stroke: Prognostic implications

Cited by 15 publications

References 41 publications

A Prospective Study of Evaluation of C - Reactive Protein in Patients of Ischemic Stroke

A Prospective Study of Evaluation of C - Reactive Protein in Patients of Ischemic Stroke

A STUDY OF HIGH SENSITIVITY C-REACTIVE PROTEIN (hs-CRP) LEVELS IN CEREBROVASCULAR ACCIDENT (STROKE)

Neutrophil-Lymphocyte Ratio and High Sensitivity C-Reactive Protein as Ischemic Stroke Outcome Predictor

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