Crown-Rump Length and Serum Human Chorionic Gonadotropin as Predictors of Gestational Age

Chervenak, Frank A.; Brightman, Rebecca C.; Thornton, John C.; Berkowitz, Gertrud S.; David, Sami S.

doi:10.1097/00006250-198602000-00010

Cited by 12 publications

(6 citation statements)

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“…Thirty‐three studies were excluded because they described growth with GA ( n = 16), assessed or compared existing chart(s) ( n = 3), were reviews or practice guidelines ( n = 3), or had other aims ( n = 11; Table S2) . Finally, 29 studies providing data on over 11 000 pregnancies met the inclusion criteria and were included in the final analysis (Table ) …”

Section: Resultsmentioning

confidence: 99%

“…The first equation that correlated CRL with GA was reported by Robinson and Fleming in 1975 . Several studies proposing and validating different CRL equations have been reported since then . Although the original Robinson equation remains widely used, there is variation in practice and no consensus exists on which formula is the most appropriate for pregnancy dating.…”

Section: Introductionmentioning

confidence: 99%

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Pregnancy dating by fetal crown–rump length: a systematic review of charts

Napolitano

Dhami

Ohuma

et al. 2014

BJOG

120

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Background Fetal crown-rump length (CRL) measurement by ultrasound in the first trimester is the standard method for pregnancy dating; however, a multitude of CRL equations to estimate gestational age (GA) are reported in the literature.Objective To evaluate the methodological quality used in studies reporting CRL equations to estimate GA using a set of predefined criteria.Search strategy Searches of MEDLINE, EMBASE, and CINAHL databases, from 1948 to 31 January 2011, and secondary reference sources, were performed.Selection criteria Observational ultrasound studies, where the primary aim was to create equations for GA estimation using a CRL measurement.Data collection and analysis Included studies were scored against predefined independently agreed methodological criteria: an overall quality score was calculated for each study.Main results The searches yielded 1142 citations. Two reviewers screened the papers and independently assessed the full-text versions of 29 eligible studies. The highest potential for bias was noted in inclusion and exclusion criteria, and in maternal demographic characteristics. No studies had systematic ultrasound quality-control measures. The four studies with the highest scores (lowest risk of bias) satisfied 18 or more of the 29 criteria; these showed lower variation in GA estimation than the remaining, lower-scoring studies. This was particularly evident at the extremes of GA.Author's conclusions Considerable methodological heterogeneity and limitations exist in studies reporting CRL equations for estimating GA, and these result in a wide range of estimated GAs for any given CRL; however, when studies with the highest methodological quality are used, this range is reduced.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Pregnancy dating by fetal crown–rump length: a systematic review of charts

Napolitano

Dhami

Ohuma

et al. 2014

BJOG

120

View full text Add to dashboard Cite

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“…The fetal crown-rump length during the first trimester has been found to be the most accurate means of dating gestational age (Robinson and Fleming, 1975;Nelson, 1981;Chervenak et al, 1986;Goldstein and Wolfson, 1994). Accurately dating gestational age is particularly important in maternal PKU.…”

Section: Discussionmentioning

confidence: 99%

Fetal Ultrasonography in Maternal Pku

et al. 1996

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Maternal phenylketonuria (PKU) is teratogenic and results in birth defects that include microcephaly, mental retardation, congenital heart disease, and intrauterine growth retardation. Treatment with a low phenylalanine diet can prevent or reduce the severity of the complications. Optimal benefit, however, requires frequent monitoring with fetal ultrasonography as a critical element. We have studied ultrasonography in 39 pregnancies enrolled in the Maternal PKU Collaborative Study and followed at our centre. First‐trimester examinations in 24 pregnancies resulted in the discovery of non‐viability in five. In each, this led to discontinuation of the difficult and expensive diet. Among the 33 pregnancies with second‐trimester evaluation, congenital heart disease was identified in five. Two of these pregnancies were terminated. Microcephaly as determined by biparietal diameter (BPD) was identified in the second trimester in only one of nine fetuses who had microcephaly at birth. Among 20 pregnancies with third‐trimester ultrasound, fetal microcephaly was identified by BPD in three of seven who had birth microcephaly. We conclude that fetal ultrasonography in maternal PKU is valuable during the first trimester in identifying non‐viable pregnancies and determining gestational age and is also valuable during the second trimester in identifying congenital heart disease and perhaps other major anomalies, but not in identifying fetal microcephaly. Third‐trimester ultrasound seems to be of limited usefulness.

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“…If the patient is in good general condition, neither prolonged bleeding nor the presence of tissue in the uterus (as detected by ultrasound) is an unequivocal indication for surgical intervention. In most cases residual products of conception will be expelled during subsequent vaginal bleeding (11,(23)(24)(25). Surgical evacuation of the uterus may be carried out on the patient's request or if the bleeding is heavy or prolonged, causes anemia, or in evidence of infection.…”

Section: Introductionmentioning

confidence: 99%

Endometrial Thickness- a Practical Prospective Marker for the Risk of Surgical Intervention after RU486 Induced Abortion

Blumenfeld

Abdallah

Kaplan

et al. 2008

Clinical medicine. Reproductive health

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Background: Medical termination of pregnancy [TOP] during the early fi rst trimester is commonly used. However, treatment failure which warrants surgical intervention occurs in small proportion of patients. Our objective was to examine the effectiveness and predictive value of sonographic measurement of endometrial thickness during a follow up visit after medical abortion as an accurate predictor of the necessity of curettage for completion of pregnancy termination.

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Crown-Rump Length and Serum Human Chorionic Gonadotropin as Predictors of Gestational Age

Cited by 12 publications

References 0 publications

Pregnancy dating by fetal crown–rump length: a systematic review of charts

Pregnancy dating by fetal crown–rump length: a systematic review of charts

Fetal Ultrasonography in Maternal Pku

Endometrial Thickness- a Practical Prospective Marker for the Risk of Surgical Intervention after RU486 Induced Abortion

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