Crown ether dopant to reduce ion suppression and improve detection in the liquid microjunction surface sampling probe
Haidy Metwally,
Jian Yu,
Rachel Theriault
et al.
Abstract:RationaleSodium and potassium are required in agar media for the growth of some microorganisms (e.g., marine bacteria). However, alkali cations are a significant source of contamination for mass spectrometry causing ion suppression and adduct formation. Conventionally, salts can be removed before mass spectrometric analysis with appropriate and often lengthy sample preparation. The direct mass spectrometric sampling of bacterial colonies grown on agar media seeks to minimize or eliminate sample preparation to … Show more
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