Crown Ether Based Optical Molecular Sensors and Photocontrolled Ionophores

Abstract

The main design concepts are reviewed for the polyfunctional crown compounds that are able to operate as optical molecular sensors or photocontrolled ionophores.

Synthesis of Dithiacrown Ethers and Evaluation of Their Cytotoxic Activity

“…[7][8][9][10][11] Indeed, macrocyclic compounds based on crown ethers proved to be interested in "host-guest" chemistry, biochemistry, phase transfer catalysis, sensor as well as in the design and synthesis of various oriented compounds with specific properties and applications. [3,[12][13][14][15] The biological properties of crown compounds are also explored. The most important properties of crown-based macrocycles are the ability to chelate with metal leading to increase of metal salt solubility and anion reactivity in non-aqueous solvents, enabling transport through the cell membrane.…”

“…Because sulfur is a “soft” atom, thiacrown ethers prefer to chelate with the ‘soft” metals like the transition metal ions (e. g., nickel, copper, iron…) and heavy metal ions (e. g., mercury, silver, lead…) [7–11] . Indeed, macrocyclic compounds based on crown ethers proved to be interested in “host‐guest” chemistry, biochemistry, phase transfer catalysis, sensor as well as in the design and synthesis of various oriented compounds with specific properties and applications [3,12–15] . The biological properties of crown compounds are also explored.…”

Effect of Interchromophoric Stacking Interactions on the Stability of the Sandwich-Type Complexes of 1-Hydroxy-9,10-anthraquinone-9-iminobenzo-15-crown-5 ether with Metal Cations

“…[4] Одним из известных свойств краун-эфиров, которое используется в супрамолекулярном дизайне, является способность образовывать сэндвичевые комплексы с от-носительно большими катионами металлов. [5][6][7] Редким классом ОМС являются таутомерные хро-моионофоры.…”

Synthesis, characterisation and ion-binding properties of oxathiacrown ethers appended to [Ru(bpy)2]2+. Selectivity towards Hg2+, Cd2+and Pb2+

“…Their selective complexing ability, which depends upon the relative size of the cavity and diameter of the cation, number of donor atoms in the crown ring and the charge of the cation has led to their use in chemosensing; this subject area has been extensively reviewed. 5,6 The selectivity in binding metal ions can be ne-tuned either by incorporating different so and hard donor atoms in the chelating ring or by modifying the exibility properties of the macrocyclic structure. This offers a tremendous potential in fabricating specic sensors for selected ions.…”