Croton zehntneri essential oil: effects on behavioral models related to depression and anxiety

Lazarini, Carlos Alberto; Uema, A.H.; Brandao, G M S; Guimarães, Ana Paula Ceolotto; Bernardi, Maria Martha

doi:10.1016/s0944-7113(00)80033-1

Cited by 30 publications

(22 citation statements)

References 14 publications

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“…General activity in the OF measures various behavioral parameters, among which are those related to emotional, exploratory, and motor behaviors. The first exposure of the animal to the OF has a more marked emotional component than the remaining aspects of exposure (Batatinha, de Souza-Spinosa, & Bernardi, 1995;Lazarini, Uema, Brandao, Guimaraes, & Bernardi, 2000;Massoco, Silva, Gorniak, Spinosa, & Bernardi, 1995;Moniz, Bernardi, & Spinosa, 1994). Thus, the decreased general activity observed in mice with acute treatment of the apolar extract could be a consequence of an increased emotional state.…”

Section: Discussionmentioning

confidence: 99%

Antidepressant-like effects of an apolar extract and chow enriched with Nepeta cataria (catnip) in mice.

Bernardi¹,

Kirsten²,

Salzgeber³

et al. 2010

Psychology & Neuroscience

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Nepeta cataria (catnip) is a plant used in pet toys and to treat human diseases. Catnip has also been used in the treatment of some depressive disorders. In this paper, we studied the antidepressant, anxiogenic, and motor activity effects of acute and repeated feeding of chow enriched with 10% N. cataria leaves and the acute and repeated administration of apolar and polar extracts of N. cataria leaves in male mice. The results showed that repeated feeding and acute and repeated administration with the apolar extract reduced immobility in the behavioral despair test but did not alter elevated plus maze and open-field parameters. Acute feeding and the acute and repeated administration of the polar extracts of N. cataria leaves did not alter the behavior of mice. These data suggest that N. cataria has antidepressant properties. Moreover, this antidepressant activity was present in the apolar extract. Keywords: open field, elevated plus maze, behavioral despair test.

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Section: Discussionmentioning

confidence: 99%

Antidepressant-like effects of an apolar extract and chow enriched with Nepeta cataria (catnip) in mice.

Bernardi¹,

Kirsten²,

Salzgeber³

et al. 2010

Psychology & Neuroscience

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“…For example, some species of the Croton genus can be cited, whose studies have confirmed its anti-inflammatory, anti-ulcerogenic, antimutagenic, anti-estrogenic and hypoglycemic (ROSA et al, 2003), antinociceptive (OLIVEIRA et al, 2001), antifungal (SOUZA et al, 2006), antibacterial RODRIGUES et al, 2009), anti-leishmaniosis (ROSA et al, 2003), anti-Trypanosoma cruzi (CAMPOS et al, 2010), larvicide (LIMA et al, 2006) and as a central nervous system depressor (LAZARINI et al, 2000).…”

Section: Introductionmentioning

confidence: 99%

Chemical composition, antibacterial and modulatory action of the essential oil of Croton rhamnifolioides leaves Pax and Hoffman

Vidal¹,

Oliveira-Tintino²,

Tintino³

et al. 2016

Biosci. J.

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ABSTRACT:The species Croton rhamnifolioides is a shrub popularly known as "quebra faca", utilized in teas or infusions for the treatment of gastrointestinal disorders as ulcers, gastric discomfort, vomiting and hemorrhagic diarrhea. This work has as its main objective to evaluate the chemical composition of the essential oil of the Croton rhamnifolioides leaves (EOC), antibacterial activity and modulatory activity of antibiotic resistance, against bacterial strains of Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa and, and antifungal activity against Candida albicans, Candida krusei and Candida tropicalis. The chemical composition was determined through chromatography with a gas phase coupled with mass spectrometry (CG/MS), whereas antimicrobial activity and modulation were determined by microdilution assay. The chemical composition of the oil revealed 21 compounds, with the major compounds being spathulenol (22.46%) and 1,8-cineol (18.32%). The antimicrobial activity was not significant with MIC>1024 µg/mL, however, was observed a synergistic interference when essential oil associated with the antibiotics aminoglycoside and β-lactam, and the antifungal polyene.

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“…al., 1991;GEORGE et. al., 1991;BATATINHA;DE SOUZA SPINOSA;BERNARDI, 1995;LAZARINI et. al., 2000;OLIVEIRA et.…”

Section: Méditerranéen De Documentation D'ensignement Et De Recherce unclassified

“…al., 1991;BERNARDI et. al., 1991;ALBUQUERQUE;SORENSON;LEALCARDOSO, 1995;BATATINHA;DE SOUZASPINOSA;BERNARDI, 1995;LAZARINI et. al., 2000;OLIVEIRA et.…”

Section: Méditerranéen De Documentation D'ensignement Et De Recherce unclassified

A aromaterapia científica na visão psiconeuroendocrinoimunológica: um panorama atual da aromaterapia clínica e científica no mundo e da psiconeuroendocrinoimunologia

Lyra¹,

Vasconcelos²

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Croton zehntneri essential oil: effects on behavioral models related to depression and anxiety

Cited by 30 publications

References 14 publications

Antidepressant-like effects of an apolar extract and chow enriched with Nepeta cataria (catnip) in mice.

Antidepressant-like effects of an apolar extract and chow enriched with Nepeta cataria (catnip) in mice.

Chemical composition, antibacterial and modulatory action of the essential oil of Croton rhamnifolioides leaves Pax and Hoffman

A aromaterapia científica na visão psiconeuroendocrinoimunológica: um panorama atual da aromaterapia clínica e científica no mundo e da psiconeuroendocrinoimunologia

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