Crosstalk of nervous and immune systems in pancreatic cancer
Fei-Fei Huang,
Wen-Hui Cui,
Lan-Yue Ma
et al.
Abstract:Pancreatic cancer is a highly malignant tumor known for its extremely low survival rate. The combination of genetic disorders within pancreatic cells and the tumor microenvironment contributes to the emergence and progression of this devastating disease. Extensive research has shed light on the nature of the microenvironmental cells surrounding the pancreatic cancer, including peripheral nerves and immune cells. Peripheral nerves release neuropeptides that directly target pancreatic cancer cells in a paracrine… Show more
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