Crossover variability and induced crossing over

Whittinghill, Maurice

doi:10.1002/jcp.1030450511

Cited by 43 publications

(9 citation statements)

References 21 publications

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“…However, a few percent crossing over in male zygotes has been confirmed, when larvae, pupae, or young adults are irradiated, and the amount of recombination in irradiated male zygotes has been found to be about equal to the increment of recombination value in irradiated female flies (Friesen, 1933;Patterson and Suche, 1934;Moriwaki, 1935Moriwaki, , 1936Whittinghill, 1955). In the present experiment, adult male flies, a few days old, were irradiated and immediately mated.…”

Section: Discussionsupporting

confidence: 49%

THE EFFECTS OF X-RAY IRRADIATION ON SELECTION RESPONSE IN <i>ôDROSOPHILA MELANOGASTER</i>

Kitagawa

1967

The Japanese journal of genetics

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One of the most important problems in population genetics concerns how much genetic variation can be induced in the polygenic systems of various organisms by exposure to radiation, and the extent to which this variation affects the process of organic evolution. However, works dealing with spontaneous or induced mutations in polygenic systems in animals as well as in plants are rather few. Buzzati-Traverso (1953) reported in Drosophila that new variation induced by X-rays in polygenic systems can be utilized for natural selection under normal laboratory conditions. He has alsoshown that a rapid increase in fitness as measured by its main components, such as the number of eggs laid and the numbers of adult offspring, accompanies this increased mutation rate. Scossiroli (1953) reported a high efficacy of artificial selection for number of sternopleural bristles after irradiation in a strain that had previously reached a plateau under selection without irradiation. More recent works by several investigators on artificial selection for the number of bristles in Drosophila have shown more effective response under irradiation than under natural conditions Robertson, 1955, 1064;Scossiroli and Scossiroli, 1959;Tobari and Nei, 1965).The purpose of the present experiment is to clarify the mechanism by which new genetic variability available for artificial selection is induced by X-rays, and to estimate the amount of increase of polygenic variability in abdominal bristle numbers. The main result of this work has already published in Yamada and Kitagawa (1961). The details of the selection experiments after irradiation is presented in this paper. MATERIALS AND EXPERIMENTAL METHODSSelection was conducted for the total number of bristles on the fourth and fifth abdominal plates of D. melanogaster. Two strains were used as the base populations.The P strain was the isogenic Oregon-R strain. The C strain consisted of F2 flies from a cross between two isogenic strains, Oregon-R and Samarkand, each having been maintained by full-sib pair mating for several hundred generations.

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Section: Discussionsupporting

confidence: 49%

THE EFFECTS OF X-RAY IRRADIATION ON SELECTION RESPONSE IN <i>ôDROSOPHILA MELANOGASTER</i>

Kitagawa

1967

The Japanese journal of genetics

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“…However, Sonnenblick does not exclude instances in Drosophila whereby all pole cells have generated from one original nucleus. Moreover, the hypothesis proposed by Whittinghill (1955) and Kidwell & Kidwell (1975) does not seem to stand for the cases of the present study where loss of chromosomes does not take place. These described earlier as 'reduced' ovaries possess normal ovarioles as well as ovarioles containing only germaria (Yannopoulos, 1978c).…”

Section: Discussioncontrasting

confidence: 67%

Comparative studies of two male recombination factors (MRF) isolated from a Southern GreekDrosophila melanogasterpopulation

1981

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A comparative study of two male recombination factors (31.1 MRF and 23 .5 MRF) isolated from the same Southern Greek natural population, revealed specific differences in their activities. 23.5 MRF induces female sterility due to atrophic ovaries at a wide range of temperatures while 31.1 MRF does so only at high temperatures. The gross morphology of the atrophic ovaries was the same and unilaterally affected pairs were found in the F x of crosses with both 23 .5 and 31.1 MRF. Furthermore, 23 .5 MRF induces: (a) lower frequencies of abnormal anaphases I and II than 31.1 MRF, (b) higher frequencies of' double crossovers' resulting from deficiences or duplications, (c) large clusters of recombinants, suggesting premeiotic origin and {d) cases where one of the non-recombinant phenotypes was not produced. Such cases have never been observed with 31.1 MRF. Moreover, the cytoplasm of the Cy L*/Pm strain that suppresses 31.1 MRF does not affect the activities of 23.5 MRF. Hypotheses to explain the different behaviour of the two factors are presented and discussed.

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“…If gonial crossing over occurred, regional differences might be amplified by the resultant clustering of recombinants and the production of double crossovers by a two-step process (Whittinghill, 1955). The observation of some clustering in male recombination data (Hiraizumi et al 1973;Kidwell & Kidwell, 1976) suggests a gonial origin for some crossover events.…”

Section: Discussionmentioning

confidence: 95%

Reciprocal differences in female recombination associated with hybrid dysgenesis inDrosophila Melanogaster

Kidwell

1977

Genet. Res.

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Large reciprocal differences in recombination frequencies were observed in F x female progeny of a number of strain crosses. These reciprocal effects on recombination were found in several intervals of all three major chromosomes; they were greatest in intervals proximal to or spanning the centromere but were also found in some distal regions. The direction of recombination change was not consistent over different chromosomal intervals. There was no clear trend for reciprocal recombination differences to be associated with change of interference values between adjacent intervals. A close association was found between reciprocal female recombination effects, male recombination and other component traits of hybrid dysgenesis. However, reciprocal differences in female recombination were not restricted to dysgenic crosses. Backcross experiments demonstrated that reciprocal differences in the centromeric region of chromosome III were the result of increased crossing-over in dysgenic F x hybrids rather than decreased crossing-over in the reciprocal hybrids. It is concluded that genotype-cytoplasm interaction can be a major factor influencing recombination frequencies and that the use of interstrain hybrids for recombination measurement may lead to errors in the estimation of intrastrain frequencies.

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Crossover variability and induced crossing over

Cited by 43 publications

References 21 publications

THE EFFECTS OF X-RAY IRRADIATION ON SELECTION RESPONSE IN <i>ôDROSOPHILA MELANOGASTER</i>

THE EFFECTS OF X-RAY IRRADIATION ON SELECTION RESPONSE IN <i>ôDROSOPHILA MELANOGASTER</i>

Comparative studies of two male recombination factors (MRF) isolated from a Southern GreekDrosophila melanogasterpopulation

Reciprocal differences in female recombination associated with hybrid dysgenesis inDrosophila Melanogaster

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