Crosslinking of poly(vinylpyrrolidone)/acrylic acid with tragacanth gum for hydrogels formation for use in drug delivery applications

Singh, Baljit; Sharma, Vikrant

doi:10.1016/j.carbpol.2016.09.086

Cited by 73 publications

(18 citation statements)

References 53 publications

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“…XRD pattern of samples showed a broad peak (at 2θ about 20°) due to amorphous nature of GT which consistent with the reported studies (Singh & Sharma, 2017;Singh, Varshney, Francis, & Rajneesh, 2016). Bassorin separation from GT resulted in lower broad peak intensity with an amorphous nature.…”

Section: Xrd Analysessupporting

confidence: 80%

Physicochemical, Rheological and Structural Characteristics of Alcohol Precipitated Fraction of Gum Tragacanth

Kurt¹

2018

Food Health

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Obtaining specific polysaccharide of gum by separating other parts appears to be an approach to get a hydrocolloid with a higher quality and new functional properties. Therefore, gum tragacanth (GT) was used for these aims. The characterization of alcohol precipitated part of GT were performed in terms of physico-chemical compositions (moisture, ash, protein, color and transparency); rheological behaviors aqueous solutions at different concentration, temperature, pH, presence of salt and sucrose; and structural characterization (FTIR, XRD, DSC and SEM). Applied process has no effect on sucrose its chemical compositions which is important for preserving of progressing application. Clearer solution was obtained for purified sample which was important for sensorial properties of end-product. Rheological experiments indicated that separation insoluble part (bassorin) from GT increased viscosity and improved the stability to the different environmental conditions. FTIR experiment results confirmed that tragacanthin and bassorin is physically mixture not chemically bonded. The improvement of thermal stability of GT was also observed by DSC as a result of bassorin separation. The results suggest that extraction soluble part of GT resulted in higher rheological and structural characteristics which may help to widen its application.

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Section: Xrd Analysessupporting

confidence: 80%

Physicochemical, Rheological and Structural Characteristics of Alcohol Precipitated Fraction of Gum Tragacanth

Kurt¹

2018

Food Health

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“…Ciprofloxacin-loaded GT based hydrogels have been reported to improve the drug delivery of diverticulitis, where GT was grafted with synthetic polymers comprising acrylic acid, PVP, ammonium persulfate (initiator) and a cross-linking agent (N,N'methylenebisacrylamide) ( Singh and Sharma, 2017). The mechanical strength and network structure of the hydrogel were affected by the pH, thereby highlighting the remarkable pHresponsive and mucoadhesive assets that could be exploited for spot-specific drug delivery applications.…”

Section: Gt Hydrogel and Electrospun Fibers-mentioning

confidence: 99%

Tree gum-based renewable materials: Sustainable applications in nanotechnology, biomedical and environmental fields

Padil

Wacławek

Černík

et al. 2018

Biotechnology Advances

122

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The prospective uses of tree gum polysaccharides and their nanostructures in various aspects of food, water, energy, biotechnology, environment and medicine industries, have garnered a great deal of attention recently. In addition to extensive applications of tree gums in food, there are substantial non-food applications of these commercial gums, which have gained widespread attention due to their availability, structural diversity and remarkable properties as 'green' bio-based renewable materials. Tree gums are obtainable as natural polysaccharides from various tree genera possessing exceptional properties, including their renewable, biocompatible, biodegradable, and non-toxic nature and their ability to undergo easy chemical modifications. This review focuses on non-food applications of several important commercially available gums (arabic, karaya, tragacanth, ghatti and kondagogu) for the greener synthesis and stabilization of metal/metal oxide NPs, production of electrospun fibers, environmental bioremediation, bio-catalysis, biosensors, coordination complexes of metal-hydrogels, and for antimicrobial and biomedical applications. Furthermore, polysaccharides acquired from botanical, seaweed, animal, and microbial origins are briefly compared with the characteristics of tree gum exudates.

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“…Hydrogels have great potential because they can absorb a large amount of water or biological fluid, and offer high porosity as well as a soft consistency. Hydrogels are known as reversible gels if molecular entanglements, such as ionic, H-bonding, or hydrophobic forces, play a key role in forming the network [3], [4]. These entanglements are often reversible and can be dissolved by changing the environmental conditions, such as the pH, ionic strength of the solution, or temperature.…”

Section: Introductionmentioning

confidence: 99%

Synthesis and characterization of bacterial cellulose and gelatin-based hydrogel composites for drug-delivery systems

Treesuppharat

Rojanapanthu

Siangsanoh

et al. 2017

Biotechnology Reports

220

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Crosslinking of poly(vinylpyrrolidone)/acrylic acid with tragacanth gum for hydrogels formation for use in drug delivery applications

Cited by 73 publications

References 53 publications

Physicochemical, Rheological and Structural Characteristics of Alcohol Precipitated Fraction of Gum Tragacanth

Physicochemical, Rheological and Structural Characteristics of Alcohol Precipitated Fraction of Gum Tragacanth

Tree gum-based renewable materials: Sustainable applications in nanotechnology, biomedical and environmental fields

Synthesis and characterization of bacterial cellulose and gelatin-based hydrogel composites for drug-delivery systems

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