Crosslinked Polymers

Matrix Assisted Synthetic Transformations: A Mosaic of Diverse Contributions. I. The Pattern Emerges

“…Later, of course, Roger Epton considerably expanded the use of the phenolic function on the support with his acrylamido-based resins, leading eventually to his ultrahigh-load method of gel-phase peptide synthesis . Roger also demonstrated how powerful 13 C NMR spectroscopy could be for monitoring reactions on highly swollen gel type supports, and in many respects he had led the way in the now more widespread use of this tool . It was 1977 when I really became aware of the great debate that had been raging between the solution synthesizers and the users of SPPS methods.…”