Crossing host boundaries: the evolutionary drivers and correlates of viral host jumps
Cedric C.S. Tan,
Lucy van Dorp,
Francois Balloux
Abstract:Most emerging and re-emerging infectious diseases stem from viruses that naturally circulate in non-human vertebrates. When these viruses cross over into humans, they can cause disease outbreaks and epidemics. While zoonotic host jumps have been extensively studied from an ecological perspective, little attention has gone into characterising the evolutionary drivers and correlates underlying these events. To address this gap, we harnessed the entirety of publicly available viral genomic data, employing a compr… Show more
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