Cross-study analyses of microbial abundance using generalized common factor methods
Molly G. Hayes,
Morgan G. I. Langille,
Hong Gu
Abstract:Background
By creating networks of biochemical pathways, communities of micro-organisms are able to modulate the properties of their environment and even the metabolic processes within their hosts. Next-generation high-throughput sequencing has led to a new frontier in microbial ecology, promising the ability to leverage the microbiome to make crucial advancements in the environmental and biomedical sciences. However, this is challenging, as genomic data are high-dimensional, sparse, and noisy.… Show more
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