Cross-Sectional Study on the Association between Pulmonary Function and Sarcopenia in Brazilian Community-Dwelling Elderly from the Amazon Region

Ohara, Daniela Gonçalves; Pegorari, Maycon Sousa; Santos, Nara Loren Oliveira dos; Silva, C. de Fátima Ribeiro; Oliveira, Mônica Silvia Rodrigues de; Matos, Areolino Pena; Jamami, Maurí­cio

doi:10.1007/s12603-019-1290-y

Cited by 32 publications

(47 citation statements)

References 29 publications

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“…For example, some conditions associated with muscle weakness such as older age, chronic disease, and cancer have been identified as risk factors for COVID-19 severity (30-32). Likewise, patients with sarcopenia have been associated with an impaired respiratory function (33), which is the function affected by SARS-CoV-2. Finally, our findings are consistent with recent studies showing that other dimensions of physical fitness are associated with an increased risk of COVID-19 hospitalization (10-13).…”

Section: Discussionmentioning

confidence: 99%

Muscle strength is associated with COVID-19 hospitalization in adults 50 years of age or older

Cheval

Sieber

Maltagliati

et al. 2021

Preprint

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Background. Muscle strength has been associated with a wide range of health outcomes. Yet, whether individuals with weaker strength are more at risk for severe COVID-19 is still unclear. The objective of this study was to investigate the independent association between muscle strength and COVID-19 hospitalization. Methods. Data from 3600 adults 50 years of age and older were analyzed using logistic models adjusted for several chronic conditions, body mass index, age, and sex. Hand grip strength was repeatedly measured between 2004 and 2017 using a handheld dynamometer. COVID-19 hospitalization during the lockdown was self-reported in summer 2020 and was used an indicator of COVID-19 severity. Results. Results showed that higher grip strength was associated with a lower risk of COVID-19 hospitalization (adjusted odds ratio [OR] per increase of 1 SD in grip strength = .64, 95% confidence interval [95% CI] = .45-.87, p = .015). Results also showed that age (OR for a 10-year period = 1.70, 95% CI = 1.32-2.20, p < .001) and obesity (OR = 2.01, 95% CI = 1.00-3.69, p = .025) was associated with higher risk of COVID-19 hospitalization. Sensitivity analyses using different measures of grip strength and robustness analyses based on rare-events logistic regression and COVID-19 patients were consistent with the main results. Conclusions. Muscle strength is an independent risk factor for COVID-19 severity in adults 50 years of age and older.

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Section: Discussionmentioning

confidence: 99%

Muscle strength is associated with COVID-19 hospitalization in adults 50 years of age or older

Cheval

Sieber

Maltagliati

et al. 2021

Preprint

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“…Vital capacity and FVC are common measurement methods for respiratory function. We adopted FVC as a measure of respiratory function, as FVC is associated with sarcopenia (39,70). As with MIP, FVC varies by body size, so it is considered adaptable to local standards (21).…”

Section: Figurementioning

confidence: 99%

Respiratory Sarcopenia and Sarcopenic Respiratory Disability: Concepts, Diagnosis, and Treatment

Nagano

Wakabayashi

Maeda

et al. 2021

The Journal of nutrition, health and aging

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The condition of muscle fiber atrophy and weakness that occurs in respiratory muscles along with systemic skeletal muscle with age is known as respiratory sarcopenia. The Japanese Working Group of Respiratory Sarcopenia of the Japanese Association of Rehabilitation Nutrition narratively reviews these areas, and proposes the concept and diagnostic criteria. We have defined respiratory sarcopenia as "wholebody sarcopenia and low respiratory muscle mass followed by low respiratory muscle strength and/or low respiratory function." Respiratory sarcopenia can be caused by various factors such as aging, decreased activity, undernutrition, disease, cachexia, and iatrogenic causes. We have also created an algorithm for diagnosing respiratory sarcopenia. Respiratory function decreases with age in healthy older people, along with low respiratory muscle mass and strength. We have created a new term, "Presbypnea," meaning a decline in respiratory function with aging. Minor functional respiratory disability due to aging, such as that indicated by a modified Medical Research Council level 1 (troubled by shortness of breath when hurrying or walking straight up hill), is an indicator of presbypnea. We also define sarcopenic respiratory disability as "a disability with deteriorated respiratory function that results from respiratory sarcopenia." Sarcopenic respiratory disability is diagnosed if respiratory sarcopenia is present with functional disability. Cases of respiratory sarcopenia without functional disability are diagnosed as "at risk of sarcopenic respiratory disability." Functional disability is defined as a modified Medical Research Council grade of 2 or more. Rehabilitation nutrition, treatment that combines rehabilitation and nutritional management, may be adequate to prevent and treat respiratory sarcopenia and sarcopenic respiratory disability.

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“…Some results from this study have been previously reported. [20][21][22] The urban population of Macapá was defined using multistage sampling with random selection of conglomerates. For the sample size calculation, the health problem was assumed to have a prevalence of 50% among the urban population of 19,955 older adults.…”

Section: Design and Samplementioning

confidence: 99%

Association between frailty syndrome and sedentary behavior among community-dwelling older adults in the Amazon region: a cross-sectional study

et al. 2021

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BACKGROUND: Existence of an association between sedentary behavior and frailty among older adults has been suggested. However, there is a lack of studies conducted in Brazil, especially in areas of the Amazon region. OBJECTIVE: To analyze the association between frailty syndrome and sedentary behavior among communitydwelling older adults. DESIGN AND SETTING: Cross-sectional study carried out in Macapá, state of Amapá, Brazil. METHODS: Frailty status was assessed using Fried's frailty phenotype, and sedentary behavior was evaluated using two questions concerning time spent in a seated position, from the International Physical Activity Questionnaire (IPAQ). A multinomial logistic regression model was used to verify the association between frailty syndrome and sedentary behavior. RESULTS: The final study sample was made up of 411 older adults with a mean age of 70.14 ± 7.25 years and an average daily duration of sedentary behavior of 2.86 ± 2.53 hours. The prevalence of non-frailty was 28.7%, prevalence of pre-frailty was 58.4% and prevalence of frailty was 12.9%. The adjusted analysis showed that there were independent associations between sedentary behavior and pre-frailty (odds ratio, OR = 1.18; 95% confidence interval, CI: 1.03-1.34) and between sedentary behavior and frailty (OR = 1.20; 95% CI: 1.02-1.40). CONCLUSION: Frailty and pre-frailty status were associated with sedentary behavior among community-dwelling older adults.

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Cross-Sectional Study on the Association between Pulmonary Function and Sarcopenia in Brazilian Community-Dwelling Elderly from the Amazon Region

Cited by 32 publications

References 29 publications

Muscle strength is associated with COVID-19 hospitalization in adults 50 years of age or older

Muscle strength is associated with COVID-19 hospitalization in adults 50 years of age or older

Respiratory Sarcopenia and Sarcopenic Respiratory Disability: Concepts, Diagnosis, and Treatment

Association between frailty syndrome and sedentary behavior among community-dwelling older adults in the Amazon region: a cross-sectional study

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