Cross-Sectional Serological Survey of Human Fascioliasis in Canutama Municipality in Western Amazon, Brazil

Abstract

Background Fascioliasis is an important parasitic disease. In the northern region of Brazil, a human parasite infection has been reported through a coprological survey. Eggs of Fasciola hepatica were found in fecal samples of 11 individuals. Knowledge of the infection in animals or the presence of snails is necessary to address the possibility of the parasite cycle occurrence in that region. The aim of this study was to describe the transmission of human fascioliasis in Canutama, Amazonas, in Western Amazonia, Brazil. Methods Serological (ELISA and Western Blot, WB) and parasitological analyses were carried out in humans. In addition, the presence of the intermediate snail host within the community was examined. Results A total of 434 human samples were included in the study, of which 36 (8.3%) were reactive by ELISA and 8 (1.8%) were reactive by WB. Fasciola hepatica eggs were found in one human sample. The occurrence of the intermediated host was recorded and 31/43 specimens were identified as Lymnaea columella. Conclusion. Canutama constitutes a focus of transmission of human fascioliasis. This study describes the first serological survey for human fascioliasis, as well as its simultaneous occurrence in human hosts and possible intermediates performed in northern Brazil.

Descriptive study of intestinal parasites in a municipality of the western Brazilian Amazon

“…infections were detected. Oliveira et al (2007) observed the prevalence of 2% Fasciola hepatica, as did we in a previous study (Maciel et al, 2018) that involved a serological survey of human fascioliasis in the same patients that constitute the population of this study, which shows the prevalence (1.8%) of F. hepatica eggs in their feces. This, however, was evidenced in a single patient and after a second collection of feces.…”

New perspectives for fascioliasis in Upper Egypt’s new endemic region: Sociodemographic characteristics and phylogenetic analysis of Fasciola in humans, animals, and lymnaeid vectors

“…Consistent with similar previous studies, a detailed clinical history was recorded for all participants regarding sociodemographic characteristics and potential sources of infection based on the characteristics of the participants and the study locality [ 35 , 36 ].…”

Human and animal fasciolosis: coprological survey in Narok, Baringo and Kisumu counties, Kenya

“…The primary definitive hosts of Fasciola parasites are the domestic ruminants (Khanjari et al 2014), while humans become accidentally infected (Nguyen et al 2018). Fasciolosis has been identified as a neglected tropical disease where over 180 million people in 75 countries are at risk of being infected (Liu et al 2014;Maciel et al 2018). Globally, over 600 million animals are at risk of getting infected with Fasciola parasites (Maciel et al 2018;Rehman et al 2016).…”

“…Fasciolosis has been identified as a neglected tropical disease where over 180 million people in 75 countries are at risk of being infected (Liu et al 2014;Maciel et al 2018). Globally, over 600 million animals are at risk of getting infected with Fasciola parasites (Maciel et al 2018;Rehman et al 2016). Fasciolosis causes massive economic burden in the livestock enterprise as a result of decreased animal productivity, characterised by reduced growth rate, low quality meat and milk, infertility and diseases (Rehman et al 2016;Shahzad et al 2012).…”