Cross‐sectional association between blood cholesterol and calcium levels in genetically diverse strains of mice
Cody M. Cousineau,
Kaelin Loftus,
Gary A. Churchill
et al.
Abstract:Genetically diverse outbred mice allow for the study of genetic variation in the context of high dietary and environmental control. Using a machine learning approach, we investigated clinical and morphometric factors that associate with serum cholesterol levels in 840 genetically unique Diversity Outbred mice of both sexes (n=417 male and 423 female), and on both a control chow (% kcals in diet: protein 22%, carbohydrate 62%, fat 16%, no cholesterol) and high fat high sucrose (% kcals in diet: protein 15%, car… Show more
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