Cross-regulation between SOX9 and the canonical Wnt signalling pathway in stem cells
Jiajia Wang,
Xichen Wan,
Qihua Le
Abstract:SOX9, a member of the SRY-related HMG-box transcription factors, has been reported to critically regulate fetal development and stem cell homeostasis. Wnt signalling is a highly conserved signalling pathway that controls stem cell fate decision and stemness maintenance throughout embryonic development and adult life. Many studies have shown that the interactions between SOX9 and the canonical Wnt signalling pathway are involved in many of the physiological and pathological processes of stem cells, including or… Show more
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