Abstract:UTMB. RATIONALE: Significant information exists on the sequences and structural details of the IgE based responses to peanut allergens. Much less work has been done to explain such a high degree of cross reactivity among various nuts. We have developed computational and experimental approaches to identify common epitopes that could contribute to cross-reactivity. METHODS: IgE and IgG4 immunanalysis of allergen proteins and peptides were performed using antibodies and sera from patients with confirmed peanut an… Show more
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