Cross-over Kidney Transplantation with Simultaneous Laparoscopic Living Donor Nephrectomy: Initial Experience

Giessing, Markus; Değer, Serdar; Roigas, Jan; Schnorr, Dietmar; Fuller, Florian; Liefeldt, Lutz; Budde, Klemens; Neumayer, Hans‐Hellmut; Loening, Stefan A.

doi:10.1016/j.eururo.2007.10.004

Cited by 5 publications

(1 citation statement)

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“…Especially the transplantation of kidneys with ‘expanded criteria' and the Eurotransplant Senior Program have increased the number of older organs for DDRT [3]. Programs for AB0-incompatible living donor renal transplantation (LDRT) and cross-over LDRT have widened the possibility for LDRT [4,5,6]. Due to the shortage of organs, kidneys of deceased pediatric donors have been transplanted to adult recipients, although this remains a rare option.…”

Section: Introductionmentioning

confidence: 99%

Outcome of Single Pediatric Deceased Donor Renal Transplantation to Adult Kidney Transplant Recipients

Friedersdorff

Fuller²,

Werthemann³

et al. 2013

Urol Int

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Introduction: In times of organ shortage more kidneys were transplanted in ‘expanded criteria kidney' programs. This study examines the outcome of adult kidney recipients from pediatric donors. Materials and Methods: This single-center retrospective analysis evaluated eight adult patients who received a kidney from a deceased pediatric donor (age 5-17) between 06/2000 and 09/2011. Results: The median donor age was 14 years (range 5-17). The median recipient age was 49 years (range 25-57). The median cold ischemia time was 13.3 h (range 4.3-20.1), while the median warm ischemia time was 53 min (range 42-60). The median follow-up was 35.8 months (range 7-142). Acute rejection was observed in 50.0% of cases. The median HLA mismatch was 2.0. The median 1-year creatinine level was 0.95 mg/dl, the uncensored 1-year graft survival was 75.0% and the 3-year graft survival 62.5%, respectively. No recipient died within the follow-up period. As severe surgical complications, one stenosis of the renal artery and one lymphocele needing surgical revision were observed. Conclusions: Renal transplantation of a deceased single pediatric donor to an adult recipient can be performed safely and shows a good outcome. Wherever feasible, single pediatric kidney transplantation can double the number of recipients over an ‘en-bloc' transplantation. The price for a single pediatric kidney transplant may be a higher vascular complication rate and a higher rejection risk. Despite the higher risks, transplantation of a single pediatric donor kidney should be performed when accomplishable.

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