Objective
A quarter of the world’s population suffers from metabolic syndrome (MetS). MetS prevalence stratifies by socioeconomic status (SES), such that low SES is associated with higher MetS risk. The present study examined the relative roles of early-life SES and current SES in explaining MetS risk.
Methods
Participants (N = 354, ages 15–55, M = 36.5 years, SD = 10.7; 55% female; 72.9% White, 16.9% Asian, 10.2% other) were evaluated for SES and MetS. All were in good health, defined as free of chronic medical illness and acute infectious disease. Using occupational status as a proxy for SES, we recruited roughly equal numbers of participants with low-low, low-high, high-low and high-high combinations of early-life and current SES. We used the International Diabetes Federation definition for MetS using race- and sex-specific cut-offs for waist circumference, triglyceride levels, HDL cholesterol, blood pressure, and HbA1c levels.
Results
Analyses revealed a main effect of low early-life SES on increased MetS risk according to three separate definitions. They included the traditional MetS diagnosis (OR=1.53, CI=1.01–2.33, p=.044), the number of MetS components for which diagnostic thresholds were met (OR=1.61, CI=1.10–2.38, p=.015), and a continuous indicator of metabolic risk based on factor analysis, F(1,350)=6.71, p=.010, partial η2=.019. There was also a significant interaction of early-life SES and current SES in predicting MetS diagnosis (OR=1.54, CI=1.02–2.34). Main effects of current SES were non-significant in all analyses.
Conclusions
These findings suggest MetS health disparities originate in childhood, which may be an opportune period for interventions.