Cross-cultural adaptation and validation of als Functional Rating Scale-Revised in Portuguese language

Guedes, K.; Pereira, C.Md.A.; Pavan, Karina; Valério, Berenice Cataldo Oliveira

doi:10.1590/s0004-282x2010000100010

Cited by 48 publications

(36 citation statements)

References 19 publications

(29 reference statements)

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“…(9) A total score on HADS for depression above 8 is highly indicative of clinically significant depression ( i.e . probable depression); the same criteria was applied for anxiety.…”

Section: Methodsmentioning

confidence: 99%

Depression and anxiety in a case series of amyotrophic lateral sclerosis: frequency and association with clinical features

Prado

Bicalho

Vidigal-Lopes

et al. 2017

Einstein (São Paulo)

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Objective To investigate the frequency of anxiety and depression and their association with clinical features of amyotrophic lateral sclerosis.Methods This is a cross-sectional and descriptive study including a consecutive series of patients with sporadic amyotrophic lateral sclerosis according to Awaji’s criteria. Patients underwent clinical and psychiatric assessment (anxiety and depression symptoms).Results We included 76 patients. The men/women ratio was 1.6:1. Participants’ mean age at disease onset was 55 years (SD±12.1). Sixty-six patients (86.8%) were able to complete psychiatric evaluation. Clinically significant anxiety was found in 23 patients (34.8%) while clinically significant depression was found in 24 patients (36.4%). When we compared patients with and without depression a significant difference was seen only in the frequency of anxiety symptoms (p<0.001). We did further analysis comparing subgroups of patients classified according to the presence or not of anxiety and or depression, without any significant difference regarding sex, age at onset, initial form, disease duration or functional measures. A positive correlation between anxiety and depressive symptoms was found (p<0.001).Conclusion Anxiety and depressive symptoms were highly correlated and frequent in patients with amyotrophic lateral sclerosis. In addition, anxiety and depression were not associated with disease duration and presentation, sex, age at onset, and functional score.

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“…(9) A total score on HADS for depression above 8 is highly indicative of clinically significant depression ( i.e . probable depression); the same criteria was applied for anxiety.…”

Section: Methodsmentioning

confidence: 99%

Depression and anxiety in a case series of amyotrophic lateral sclerosis: frequency and association with clinical features

Prado

Bicalho

Vidigal-Lopes

et al. 2017

Einstein (São Paulo)

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“…When the MIC was equal to the FVC, it was considered to indicate the presence of bulbar muscle dysfunction. The Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised (ALSFRS-R/BR) 16 and the Amyotrophic Lateral Sclerosis Assessment Questionnaire (ALSAQ-40/BR) 17 were also administered. The ALSFRS-R/BR is scored from 0–48, where a lower score indicates worse function, while the ALSAQ-40/BR has scores of 0–100, in which higher scores indicate a worse quality of life.…”

Section: Methodsmentioning

confidence: 99%

Effects of non-invasive ventilation and posture on chest wall volumes and motion in patients with amyotrophic lateral sclerosis: a case series

Magalhães¹,

Fregonezi²,

Vidigal-Lopes³

et al. 2016

Braz. J. Phys. Ther.

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BackgroundThe effects of non-invasive ventilation (NIV) on the breathing pattern and thoracoabdominal motion of patients with amyotrophic lateral sclerosis (ALS) are unknown.Objectives1) To analyze the influence of NIV on chest wall volumes and motion assessed by optoelectronic plethysmography in ALS patients and 2) to compare these parameters in the supine and sitting positions to those of healthy individuals (without NIV).MethodNine ALS patients were evaluated in the supine position using NIV. In addition, the ALS patients and nine healthy individuals were evaluated in both sitting and supine positions. Statistical analysis was performed using the paired Student t-test or Wilcoxon test and the Student t-test for independent samples or Mann-Whitney U test.ResultsChest wall volume increased significantly with NIV, mean volume=0.43 (SD=0.16)L versus 0.57 (SD=0.19)L (p=0.04). No significant changes were observed for the pulmonary rib cage, abdominal rib cage, or abdominal contribution. The index of the shortening velocity of the diaphragmatic muscle, mean=0.15 (SD=0.05)L/s versus 0.21 (SD=0.05)L/s (p<0.01), and abdominal muscles, mean=0.09 (SD=0.02)L/s versus 0.14 (SD=0.06)L/s (p<0.01), increased during NIV. Comparisons between the supine and sitting positions showed similar changes in chest wall motion in both groups. However, the ALS patients presented a significantly lower contribution of the abdomen in the supine position compared with the controls, mean=56 (SD=13) versus 69 (SD=10) (p=0.02).ConclusionsNIV improved chest wall volumes without changing the contribution of the chest wall compartment in ALS patients. In the supine position, ALS patients had a lower contribution of the abdomen, which may indicate early diaphragmatic dysfunction.

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“…Case group patients were clinically characterized in terms of symptom onset (bulbar or spinal), symptom duration (in months), feeding pathway (oral and/or enteral) and score on the ALS functional rating scale (ALSFRS) (7). This instrument assesses the motor, bulbar and respiratory function of these patients, serving as a prognostic indicator.…”

Section: Clinical and Nutritional Datamentioning

confidence: 99%

Dietary intake and zinc status in amyotrophic lateral sclerosis

et al. 2017

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ResumenIntroducción: hay pruebas considerables de que los cambios en la homeostasis del zinc están relacionados con la patogénesis de la esclerosis lateral amiotrófica (ELA) y que la malnutrición es un factor pronóstico capaz de reducir la supervivencia de los pacientes con ELA. Objetivo: evaluar la ingesta dietética y el estado de zinc en pacientes con ELA, tratados en un centro de atención ambulatoria especializado en Natal, Brasil. Métodos: se incluyeron 20 pacientes con ELA (grupo de casos) y 37 sujetos sanos (grupo control). Se realizaron evaluaciones clínicas y antropométricas y se obtuvo la ingesta dietética en dos recordatorios de 24 horas. Las concentraciones plasmáticas y urinarias de zinc se determinaron por espectrofotometría de absorción atómica. Resultados: la mayoría de los participantes fueron eutróficos. El consumo medio de energía, proteínas, carbohidratos y grasas fue significativamente menor en el grupo de casos. Hubo una mayor prevalencia de ingesta inadecuada de zinc en el grupo de casos (35%) en comparación con los controles (27%). El zinc plasmático medio fue significativamente menor en el grupo de casos que en los controles (77,13 ± 22,21 frente a 87,84 ± 17,44 μgZn/dl). El zinc urinario no difirió significativamente entre los casos y los controles. En el grupo de casos, las concentraciones de zinc plasmático y urinario fueron inferiores a los valores de referencia en el 50,0% y 52,6% de los pacientes, respectivamente. Conclusión: gran parte de los pacientes con ELA exhibieron una ingesta dietética pobre y modificación en el estatus de zinc corporal. La deficiencia de zinc encontrada en la mitad de los pacientes con ELA puede contribuir a un empeoramiento del pronóstico y debe ser el objetivo de la intervención nutricional que apunta a corregir esta deficiencia. AbstractBackground: There is considerable evidence that abnormal zinc homeostasis is related to amyotrophic lateral sclerosis (ALS) pathogenesis, and malnutrition is an independent prognostic factor for worsened survival of ALS patients. Objective: To evaluate the dietary intake and zinc status in patients with ALS, treated in a specialized outpatient facility in Natal, Brazil. Methods: Twenty patients with ALS (case group) and 37 healthy subjects (control group) were included. Clinical and anthropometric assessments were carried out and dietary intake was obtained from two 24-hour recalls. Plasma and urinary zinc concentrations were determined by atomic absorption spectrophotometry. Results: Most of the participants were eutrophic. Mean energy, protein, carbohydrate and fat intake was significantly lower for the case group. There was greater prevalence of inadequate zinc intake in the case group (35%) compared to controls (27%). Mean plasma zinc was significantly lower in the case group than in controls (77.13 ± 22.21 vs 87.84 ± 17.44 µgZn/dl). Urinary zinc did not differ significantly between cases and controls. In the case group, plasma and urinary zinc concentrations were below reference values in 50.0% and 52.6% of patients,...

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Cross-cultural adaptation and validation of als Functional Rating Scale-Revised in Portuguese language

Cited by 48 publications

References 19 publications

Depression and anxiety in a case series of amyotrophic lateral sclerosis: frequency and association with clinical features

Depression and anxiety in a case series of amyotrophic lateral sclerosis: frequency and association with clinical features

Effects of non-invasive ventilation and posture on chest wall volumes and motion in patients with amyotrophic lateral sclerosis: a case series

Dietary intake and zinc status in amyotrophic lateral sclerosis

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