Cross-cultural adaptation and validation of the `Multiple Sclerosis Quality of Life Instrument' in Hungarian

Abstract

Health-related quality of life measurements are gaining more importance in the study and clinical practice of multiple sclerosis. The aim of our study was the adaptation of the Multiple Sclerosis Quality of Life Instrument (MSQOL-54) in Hungarian. The study was carried out at the Department of Neurology, University of Szeged and two other multiple sclerosis centers. The Hungarian translation of the questionnaire was given to patients at the outpatient units of the neurology departments. The EDSS score of the patients were determined and data concerning the onset and the clinical form of the disease was collected. Altogether 438 patients filled out the questionnaire. We enrolled patients with all clinical forms of the disease. Cronbach's alpha coefficients were over 0.8 in case of all scales except ;Rolelimitations - emotional' (0.794), indicating a good internal consistency reliability for group comparisons. The instrument was able to distinguish between known clinical group differences. The Hungarian version of the MSQOL-54 instrument shows good psychometric properties similar to the original questionnaire.

Translation of the Multiple Sclerosis Quality of Life-54: Brazilian Version

“…This can also be observed in other studies on translations of the MSQoL-54 [10][11][12][13][14], including the original [4]. Among these, some also observed that the highest percentage of items with no response on sexual function and satisfaction with sexual function come from female patients [10,12,14]. This differs from our results where the proportion was 1:1, but in a smaller sample than that of the validation.…”

“…This was not an interpretation, embarrassment, or misunderstanding problem, but rather because they had not had sexual intercourse in the last four weeks. This can also be observed in other studies on translations of the MSQoL-54 [10][11][12][13][14], including the original [4]. Among these, some also observed that the highest percentage of items with no response on sexual function and satisfaction with sexual function come from female patients [10,12,14].…”

“…This instrument, the MSQoL-54, was translated into multiple languages [4,[7][8][9][10][11][12][13][14] and has since been one of the most utilized questionnaires in the scientific community.…”

Measuring health-related quality of life in Hungarian children attending a cardiology clinic with the Pediatric Quality of Life Inventory™

“…Patient-reported outcome (PRO) studies, including HRQoL studies, have not appeared in Hungary until the recent years and were mainly carried out in adult populations [12][13][14][15][16][17][18][19][20]. As the standards of care and results of medical care of children with heart disease in Hungary correspond to international recommendations, we considered it important to assess the outcomes of Hungarian pediatric cardiology care from the patients' point of view.…”

Analyses of measuring tools comparing the quality of life in patients with multiple sclerosis

“…Description of MS-specific instruments used in the assessment of health-related quality of life (1) Comparing several selected studies evaluating the quality of life in patients with MS (MSQOL); the differences in overall quality of life were found to be minimal. The overall quality of life in patients was evaluated as 50.50 (5), 59.39 (8), 58.20 (13) (Table 3).…”