Cross-calibration of GE/Lunar pencil and fan-beam dual energy densitometers—bone mineral density and body composition studies

Oldroyd, B.; Smith, A.H.; Truscott, J G

doi:10.1038/sj.ejcn.1601633

Cited by 69 publications

(60 citation statements)

References 30 publications

(23 reference statements)

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“…Elsewhere, and also using the more recent iDXA model, precision for TBL measurements have also been reported as excellent, with CVs of 0.4% (Rezzi et al, 2009), 0.52% (Faulkner et al, 2006) and 0.55% (Krueger et al, 2006).We also found excellent precision for the measurement of BMC, TBF and %TBF, compared with values reported elsewhere for older models of DXA and in a range of participants (Economos et al, 1997;Figueroa-Colon et al, 1998;Oldroyd et al, 2003). In this study, precision values for body composition parameters are comparable with those reported by studies elsewhere, which have also used the iDXA.…”

Section: Resultssupporting

confidence: 60%

“…There were large margins in CVs between machines for TFM (iDXA: 0.8%, Prodigy: 2.5%) and %TBF (iDXA: 0.9%, Prodigy: 2.7%). Although it should be considered that the participants measured in this study were generally larger in body size (BMI: 25.8 (5.1) vs 21.6 (4.4) kg/m 2 ) (Oldroyd et al, 2003), the results would imply superior reproducibility of the iDXA for the measurement of body composition.…”

Section: Resultsmentioning

confidence: 95%

“…the Prodigy and DPX-L to be 0.8 and 1.0%, respectively, (Oldroyd et al, 2003). Elsewhere, and also using the more recent iDXA model, precision for TBL measurements have also been reported as excellent, with CVs of 0.4% (Rezzi et al, 2009), 0.52% (Faulkner et al, 2006) and 0.55% (Krueger et al, 2006).We also found excellent precision for the measurement of BMC, TBF and %TBF, compared with values reported elsewhere for older models of DXA and in a range of participants (Economos et al, 1997;Figueroa-Colon et al, 1998;Oldroyd et al, 2003).…”

Section: Resultsmentioning

confidence: 99%

“…4.4, range 12.0-34.7) kg/m 2 , using the GE Lunar Prodigy fan beam DXA model (Oldroyd et al, 2003). In this study, we report improved precision using the iDXA, with CVs ranging between 0.5 and 0.86%, compared with those for the Prodigy (0.8-2.7%) (Oldroyd et al, 2003). There were large margins in CVs between machines for TFM (iDXA: 0.8%, Prodigy: 2.5%) and %TBF (iDXA: 0.9%, Prodigy: 2.7%).…”

Section: Resultsmentioning

confidence: 99%

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In vivo precision of the GE Lunar iDXA densitometer for the measurement of total body composition and fat distribution in adults

2010

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In vivo precision for body composition measurements using dual energy X-ray absorptiometry (DXA; GE Lunar iDXA, GE Healthcare, Bucks, UK) was evaluated in 52 men and women, aged 34.8 (s.d. 8.4; range 20.1-50.5) years, body mass index (25.8 kg/m 2 ; range 16.7-42.7 kg/m 2 ). Two consecutive total body scans (with re-positioning) were conducted. Precision was excellent for all measurements, particularly for total body bone mineral content and lean tissue mass (root mean square 0.015 and 0.244 kg; coefficients of variation (CV) 0.6 and 0.5%, respectively). Precision error was CV 0.82% for total fat mass and 0.86% for percentage fat. Precision was better for gynoid (root mean square 0.397 kg; CV 0.96%) than for android fat distribution (root mean square 0.780 kg, CV 2.32%). There was good agreement between consecutive measurements for all measurements (slope (s.e.) 0.993-1.002; all R 2 ¼ 0.99). The Lunar iDXA provided excellent precision for total body composition measurements. Research into the effect of body size on the precision of DXA body fat distribution measurements is required.

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Section: Resultssupporting

confidence: 60%

Section: Resultsmentioning

confidence: 95%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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In vivo precision of the GE Lunar iDXA densitometer for the measurement of total body composition and fat distribution in adults

2010

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“…Previous studies have evaluated relationships between DPX devises and the newer narrow fan bean densitometers (Prodigy). In general, small differences between the two types of absorptiometry were found, and by use of cross-calibration equations and factors, results from the two different devices were considered compatible [19,20].…”

Section: Discussionmentioning

confidence: 99%

The Tromsø Study: Fit Futures: a study of Norwegian adolescents’ lifestyle and bone health

et al. 2014

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Summary Bone mass achievement predicts later fracture risk. This population-based study describes bone mineral density levels (BMD) and associated factors in Norwegian adolescents. Compared with international reference ranges, BMD levels appear higher and physical activity levels are positively associated with BMD.Purpose Norway has one of the highest reported incidences of osteoporotic fractures. Maximization of peak bone mass may prevent later fractures. This population-based study compared BMD levels of Norwegian adolescents with international reference ranges and explored associated factors.Methods All first year upper secondary school students, aged 15-19 years in the Tromsø region were invited to the Fit Futures study in 2010-2011. Over 90% of the invited participants attended, 508 girls and 530 boys. BMD was measured at total hip, femoral neck and total body by dual x-ray absorptiometry.Lifestyle variables were collected by self-administered questionnaires and interviews. All analyses were performed sex stratified, using linear regression models.Results In girls mean BMD (SD) was 1.060 (0.124), 1.066 (0.123) and 1.142 (0.077) g/cm² at the total hip, femoral neck and total body respectively. In boys corresponding values were 1.116 (0.147), 1.103 (0.150) and 1.182 (0.097), with significant higher values than the Lunar pediatric reference at 16 years of age In girls, height and self-reported intensive physical activity of more than four hours a week and early sexual maturation were positively associated with BMD at both femoral sites (p<0.047). Among boys age, height, body mass index, physical activity and alcohol intake were positively (p<0.038), whereas early stages of sexual maturation and smoking was negatively (p<0.047) related to BMD.Conclusions Despite the heavy fracture burden, Norwegian adolescents´ BMD levels are higher than agematched Caucasians. Physical activity is associated with 1 SD increased BMD levels in those involved in competition or hard training.

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Precision of a new tool to measure visceral adipose tissue (VAT) using dual‐energy X‐Ray absorptiometry (DXA)

Rothney

Xia

Wacker

et al. 2013

Obesity

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Objective: A new tool to quantify visceral adipose tissue (VAT) over the android region of a total body dual-energy x-ray absorptiometry (DXA) scan has recently been reported. The measurement, CoreScan, is currently available on Lunar iDXA densitometers. The purpose of the study was to determine the precision of the CoreScan VAT measurement, which is critical for understanding the utility of this measure in longitudinal trials. Design and Methods: VAT precision was characterized in both an anthropomorphic imaging phantom (measured on 10 Lunar iDXA systems) and a clinical population consisting of obese women (n ¼ 32). Results: The intrascanner precision for the VAT phantom across 9 quantities of VAT mass (01,800 g) ranged from 28.4 to 38.0 g. The interscanner precision ranged from 24.7 to 38.4 g. There was no statistical dependence on the quantity of VAT for either the inter-or intrascanner precision result (p ¼ 0.670). Combining inter-and intrascanner precision yielded a total phantom precision estimate of 47.6 g for VAT mass, which corresponds to a 4.8% coefficient of variance (CV) for a 1 kg VAT mass. Our clinical population, who completed replicate total body scans with repositioning between scans, showed a precision of 56.8 g on an average VAT mass of 1110.4 g. This corresponds to a 5.1% CV. Hence, the in vivo precision result was similar to the phantom precision result. Conclusions: The study suggests that CoreScan has a relatively low precision error in both phantoms and obese women and therefore may be a useful addition to clinical trials where interventions are targeted towards changes in visceral adiposity.Obesity (2013) 21, E134-E136.

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Cross-calibration of GE/Lunar pencil and fan-beam dual energy densitometers—bone mineral density and body composition studies

Cited by 69 publications

References 30 publications

In vivo precision of the GE Lunar iDXA densitometer for the measurement of total body composition and fat distribution in adults

In vivo precision of the GE Lunar iDXA densitometer for the measurement of total body composition and fat distribution in adults

The Tromsø Study: Fit Futures: a study of Norwegian adolescents’ lifestyle and bone health

Precision of a new tool to measure visceral adipose tissue (VAT) using dual‐energy X‐Ray absorptiometry (DXA)

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