Cross-Calibration and Minimum Precision Standards for Dual-Energy X-ray Absorptiometry: The 2005 ISCD Official Positions

Shepherd, John; Lü, Ying; Wilson, Kevin E.; Fuerst, Thomas; Genant, Harry K.; Hangartner, Thomas N.; Wilson, Charles R.; Hans, Didier; Leib, Edward S.

doi:10.1016/j.jocd.2006.05.005

Cited by 127 publications

(38 citation statements)

References 67 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The International Society for Clinical Densitometry recommends in vivo calibration when BMD from different models or makes are quantitatively compared [21]. We followed this recommendation and adjusted our data according to our own vivo calibration studies.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Regional differences in hip bone mineral density levels in Norway: the NOREPOS study

et al. 2008

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

“…Considering the small variation in population BMD, uncalibrated results from different DXA devices can easily result in wrong conclusions when comparing BMD in different populations. The International Society for Clinical Densitometry recommends cross-calibration before BMD from different models or makes are quantitatively compared [21].…”

Section: Introductionmentioning

confidence: 99%

Regional differences in hip bone mineral density levels in Norway: the NOREPOS study

et al. 2008

View full text Add to dashboard Cite

show abstract

“…Crosscalibration study of all three facilities was performed by having one technologist do ten phantom scans with repositioning, as recommended by the ISCD for the systems with the same technology (manufacturer and model; Shepherd et al 2006). We found a negligible difference in mean BMD between facilities, so a correction factor was not considered necessary.…”

Section: Bmd Measurementmentioning

confidence: 99%

The combinations of polymorphisms in vitamin D receptor, osteoprotegerin and tumour necrosis factor superfamily member 11 genes are associated with bone mineral density

Mencej-Bedrač¹,

Preželj²,

Kocjan³

et al. 2009

Journal of Molecular Endocrinology

View full text Add to dashboard Cite

1a,25-dihydroxyvitamin D 3 upregulates tumour necrosis factor superfamily member 11 (TNFSF11) that codes for the receptor activator of nuclear factor kB ligand (RANKL), and downregulates osteoprotegerin (OPG) expression. We have analyzed the individual effects of polymorphisms in the vitamin D receptor gene (VDR), OPG and TNFSF11, and searched for interactions between them. Six hundred and forty one subjects were evaluated: 239 osteoporotic and 228 non-osteoporotic post-menopausal, 57 pre-menopausal women and 117 elderly men. The subjects were genotyped for BsmI, FokI and Cdx2 in VDR, K3N in OPG and K290COT, K643COT and K693GOC in TNFSF11 gene. Bone mineral density (BMD) and biochemical markers were measured. In the osteoporotic women, femoral neck BMD (BMD-fn)showed associations with BsmI(VDR) and Cdx2(VDR) (PZ0 . 015 and 0 . 047 respectively), and lumbar spine BMD (BMDls) with K3N(OPG) and K290COT(TNFSF11) (PZ0 . 021 and 0 . 017). No association with BMD was found in the nonosteoporotic women. In the pre-menopausal women, the Cdx2(VDR) polymorphism was associated with BMD-fn and total hip BMD (PZ0 . 011 and 0 . 011). In elderly men, FokI(VDR) was associated with BMD-fn and BMD-ls (PZ0 . 040 and 0 . 036). Interestingly, the K290COT(TNFSF11)-K3N(OPG) combination was associated with BMD-th (PZ0 . 041) in the osteoporotic women. In the non-osteoporotic women, the combination K3N(OPG)-Cdx2(VDR) was associated with BMD-ls, BMD-th and BMD-fn (PZ0 . 032, 0 . 049 and 0 . 022), and the combination K290COT(TNFSF11)-K3N(OPG) with BMD-fn (PZ0 . 029). For the first time, the presence of gene-gene interactions between VDR, OPG and TNFSF11 genes was studied. Our results strongly suggest further confirmation of their combined influence on larger cohorts.

show abstract

“…Precision errors are partly dependent on quality assurance systems to detect scanner changes and on operators' training and experience [2]. The evaluation of precision errors involves repeated measurements, with the International Society of Clinical Densitometry (ISCD) recommending either duplicate scans of 30 subjects or triplicate scans of 15 subjects [3] [4]. Precision errors may vary between individuals due to differences in bone status and biological variations, such as tissue inhomogeneity, and it is therefore important to measure a representative set of subjects [5].…”

Section: Introductionmentioning

confidence: 99%

Obesity Increases Precision Errors in Dual-Energy X-Ray Absorptiometry Measurements

Knapp

Welsman

Hopkins

et al. 2012

Journal of Clinical Densitometry

View full text Add to dashboard Cite

The precision errors of dual energy x-ray absorptiometry (DXA) measurements are important for monitoring osteoporosis. This study investigated the effect of body mass index (BMI) on precision errors for lumbar spine, femoral neck, total hip and total body bone mineral density (n=28) BMI groups respectively were: lumbar spine BMD: 0.99%, 1.30% and 1.68%; femoral neck BMD: 1.32%, 1.37% and 2.00%; total hip BMD: 0.85%, 0.88% and 1.06%; total body BMD: 0.66%, 0.73% and 0.91%. Statistically significant differences in precision error between the normal and obese groups were found for lumbar spine (P = 0.0006), femoral neck (P = 0.005) and total body BMD (P = 0.025). These results suggest that serial measurements in obese subjects should be treated with caution since the least significant change may be larger than anticipated.

show abstract

Cross-Calibration and Minimum Precision Standards for Dual-Energy X-ray Absorptiometry: The 2005 ISCD Official Positions

Cited by 127 publications

References 67 publications

Regional differences in hip bone mineral density levels in Norway: the NOREPOS study

Regional differences in hip bone mineral density levels in Norway: the NOREPOS study

The combinations of polymorphisms in vitamin D receptor, osteoprotegerin and tumour necrosis factor superfamily member 11 genes are associated with bone mineral density

Obesity Increases Precision Errors in Dual-Energy X-Ray Absorptiometry Measurements

Contact Info

Product

Resources

About