Cross-aldol reaction of 3-acetyl-2H-chromen-2-one by using Amberlyst 26A as catalyst

Coumarin‐Chalcones Generated from 3‐Acetylcoumarin as a Promising Agent: Synthesis and Pharmacological Properties

“…Moreover, other catalysts such as bismuth triflate [Bi-(OTf) 3 ], [74] Amberlyst 26 A [75] and zinc oxide nanoparticles incorporated on a graphitic carbon nitride nanocomposite (ZnS NPs/g-C 3 N 4 ), [76] are used to produce various chalcones. A proposed mechanism [76] for the reaction is presented in Scheme 2.…”

“…When thiazolylpyrazolyl coumarin ( 70) is refluxed with chloroacetone (71), or phenacyl bromide (73); ethyl-2-chloroacetoacetate (75) and ethylbromoacetate (77), or ethyl 2-bromopropionate (79) in ethanol, with a catalytic amount of anhydrous sodium acetate, produces the 4-methyl/phenylthiazolyl pyrazoline derivatives ( 72) and ( 74), ethyl-2-pyrazolyl-4-methylthiazole-5-carboxylate (76) and pyrazolyl thiazolidinones (78) and ( 80) in good yields. The target compound ( 82) is made by combining thiocarbamoyl pyrazolines (70) and the suitable hydrazonoyl chlorides (81) with triethylamine in a one-pot Scheme 14.…”

Cytotoxic and apoptotic potential of some coumarin and 2-amino-3-carbonitrile selenophene derivatives in prostate cancer

“…Coumarin compounds are biologically active compounds that can be isolated from plants as well as synthetically synthesized in laboratories [1]. It has been determined by various studies have shown that Coumarin exhibit antiviral [2,3], antioxidant [4], anticonvulsant [5,6], anticancer [7][8][9][10], and also shows AcHE and BucHE enzyme inhibition activity [11][12][13][14][15].…”