Crohn′s disease in a Saudi outpatient population: Is it still rare?

Al-Mofarreh, Mohammad A; Mofleh, Ibrahim A Al; Al-Teimi, Ibrahim N.; Aljebreen, Abdulrahman

doi:10.4103/1319-3767.45357

Cited by 17 publications

(23 citation statements)

References 29 publications

(40 reference statements)

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“…15 In the Kingdom of Saudi Arabia (KSA), IBD, which was rarely diagnosed several decades ago, is increasingly reported in both adults and children. [16][17][18][19][20][21][22][23] However, with the exception of a recent publication from China, 15 there is a lack of information on the incidence of pediatric IBD in developing countries. 24 Therefore, the objective of this report is to establish the incidence and trend of IBD in Saudi Arabian children over time.…”

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confidence: 99%

Incidence of Pediatric Inflammatory Bowel Disease in Saudi Arabia

Mouzan

Saadah

Alsaleem

et al. 2014

Inflammatory Bowel Diseases

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confidence: 99%

Incidence of Pediatric Inflammatory Bowel Disease in Saudi Arabia

Mouzan

Saadah

Alsaleem

et al. 2014

Inflammatory Bowel Diseases

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“…[17] The Arab countries are not excluded and several studies mainly from KSA over the last three decades have shown an increasing trend. [18–26]…”

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confidence: 99%

Emerging inflammatory bowel disease in saudi outpatients: A report of 693 cases

Al-Mofarreh

Al-Mofleh

2013

Saudi J Gastroenterol

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Background/Aim:Inflammatory bowel disease (IBD) is a chronic disease of unknown etiology and considered traditionally as a disease of the western world. Recently, rising trends have been observed in countries previously known to have a low prevalence and incidence. The aim of this study is to collect epidemiological data on IBD outpatients and to add data from the Kingdom of Saudi Arabia (KSA) to the available IBD literature.Patients and Methods:The medical records of 693 Saudi patients with IBD over a period of 17 years, between 1993 and 2009, were reviewed. The demographic and clinical data and methods of diagnosis were retrieved.Results:The total number of patients in this cohort was 693. It constituted 238 (34.3%) ulcerative colitis (UC) and 455 (65.7%) Crohn's disease (CD) patients. UC was steady throughout the years, whereas only 1.2 CD patients were diagnosed per year in the first 11 years, and 73.7 per year in the last six years. The median age of UC patients was 34 years, ranging from 10 to 80 years with a peak between 21 and 40 years and in CD it was 27 years, ranging from 11 to 73 years with a peak between 11 and 30 years. There was a male preponderance of 1.5:1 and 2:1, respectively. The rest of the data is discussed in this study.Conclusion:IBD is no longer a rare disease in KSA. UC is in a steady state, whereas CD is increasing significantly and far outnumbering UC.

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“…In Middle East two decades back, CD was viewed as extremely uncommon; yet numerous current reports from various focuses in Saudi Arabia and other Arab nations propose a high rate increase in CD incidence and commonness in this area [8][9][10]. 25 years ago, it was believed that CD does not exist in the KSA [11]. In Saudi Arabia CD is reported frequently.…”

Section: Discussionmentioning

confidence: 99%

Extra-Intestinal Complications (EIC) and Manifestations (EIM) (Ocular and Pulmonary) among Patients with Crohn's Disease

Ali¹,

Bamahfouz²,

Krema³

et al. 2017

J Gastrointest Dig Syst

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Crohn's disease (CD) is an immune-mediated disorder of unknown etiology primarily affect the gastrointestinal tract with series of extra intestinal manifestations (EIM) and Extra intestinal complications (EIC) that affects different organs and systems. EIMs are capable of involving nearly every system in the body; some believe that IBD is a systemic disorder with predominantly bowel manifestations. EI complications are mainly caused by the disease itself that induce mal-absorption with consequent micronutrient deficiencies, osteoporosis, peripheral neuropathies, kidney stones, gallstones and IBD drug-related side effects. In Saudi Arabia, CD is reported frequently. In this review, we try to make stress on different previously reported frequencies of EIMs and EIC in patients with CD; from our point of view we make an overview on the ocular and pulmonary complications and manifestations that are related either to disease activity or an indication of the presence of CD. Scleritis, uveitis and dry eye syndrome in previous healthy subjects with intestinal manifestation help in early diagnosis of CD especially in unexpected ages of the diseases. Further work on pulmonary manifestations to make full explanation on whether pulmonary disease is secondary to the drugs or to the underlying disease process.

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Crohn′s disease in a Saudi outpatient population: Is it still rare?

Cited by 17 publications

References 29 publications

Incidence of Pediatric Inflammatory Bowel Disease in Saudi Arabia

Incidence of Pediatric Inflammatory Bowel Disease in Saudi Arabia

Emerging inflammatory bowel disease in saudi outpatients: A report of 693 cases

Extra-Intestinal Complications (EIC) and Manifestations (EIM) (Ocular and Pulmonary) among Patients with Crohn's Disease

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