Critical review on recent developments in solventless techniques for extraction of analytes

Nerı́n, Cristina; Salafranca, Jesús; Aznar, María Pilar Matud; Batlle, Ramón

doi:10.1007/s00216-008-2437-6

Cited by 258 publications

(144 citation statements)

References 270 publications

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“…CAR/PDMS extracts with high efficiency ethyl hexanoate (6), p-cymene (9), (Z)-3-hexen-1-ol (13), 2-acetylfuran (24), whereas PDMS is more indicated to extract 1-dodecene (19), decanal (22), ␣-ionol (43), diethyl malate (46), and octanoic (47), tetradecanoic (55), and hexadecanoic acids (56). PA …”

Section: Hs-spme Analysismentioning

confidence: 99%

“…Is a miniaturization of the conventional SPE in which the sample volume and volumes for extraction and washing solvents are reduced compared to SPE technique [19] (Table 2). A wide range of sorbents are available including C 2 , C 8 and C 18 bonded phases on silica, polymeric resins (polystyrene/divinylbenzene copolymer), molecular imprinted polymers (MIPs), polar sorbents such as silica and ion-exchange sorbents, and mixed-mode sorbents.…”

Section: Introductionmentioning

confidence: 99%

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Effectiveness of high-throughput miniaturized sorbent- and solid phase microextraction techniques combined with gas chromatography–mass spectrometry analysis for a rapid screening of volatile and semi-volatile composition of wines—A comparative study

Mendes¹,

Gonçalves²,

Câmara³

2012

Talanta

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a b s t r a c tIn this study the feasibility of different extraction procedures was evaluated in order to test their potential for the extraction of the volatile (VOCs) and semi-volatile constituents (SVOCs) from wines. In this sense, and before they could be analysed by gas chromatography-quadrupole first stage masss spectrometry (GC-qMS), three different high-throughput miniaturized (ad)sorptive extraction techniques, based on solid phase extraction (SPE), microextraction by packed sorbents (MEPS) and solid phase microextraction (SPME), were studied for the first time together, for the extraction step. To achieve the most complete volatile and semi-volatile signature, distinct SPE (LiChrolut EN, Poropak Q, Styrene-Divinylbenzene and Amberlite XAD-2) and MEPS (C 2 , C 8 , C 18 , Silica and M1 (mixed C 8 -SCX)) sorbent materials, and different SPME fibre coatings (PA, PDMS, PEG, DVB/CAR/PDMS, PDMS/DVB, and CAR/PDMS), were tested and compared. All the extraction techniques were followed by GC-qMS analysis, which allowed the identification of up to 103 VOCs and SVOCs, distributed by distinct chemical families: higher alcohols, esters, fatty acids, carbonyl compounds and furan compounds. Mass spectra, standard compounds and retention index were used for identification purposes.SPE technique, using LiChrolut EN as sorbent (SPE LiChrolut EN ), was the most efficient method allowing for the identification of 78 VOCs and SVOCs, 63 and 19 more than MEPS and SPME techniques, respectively. In MEPS technique the best results in terms of number of extractable/identified compounds and total peak areas of volatile and semi-volatile fraction, were obtained by using C 8 resin whereas DVB/CAR/PDMS was revealed the most efficient SPME coating to extract VOCs and SVOCs from Bual wine. Diethyl malate (18.8 ± 3.2%) was the main component found in wine SPE LiChrolut EN extracts followed by ethyl succinate (13.5 ± 5.3%), 3-methyl-1-butanol (13.2 ± 1.7%), and 2-phenylethanol (11.2 ± 9.9%), while in SPME DVB/CAR/PDMS technique 3-methyl-1-butanol (43.3 ± 0.6%) followed by diethyl succinate (18.9 ± 1.6%), and 2-furfural (10.4 ± 0.4%), are the major compounds. The major VOCs and SVOCs isolated by MEPS C8 were 3-methyl-1-butanol (26.8 ± 0.6%, from wine total volatile fraction), diethyl succinate (24.9 ± 0.8%), and diethyl malate (16.3 ± 0.9%). Regardless of the extraction technique, the highest extraction efficiency corresponds to esters and higher alcohols and the lowest to fatty acids.Despite some drawbacks associated with the SPE procedure such as the use of organic solvents, the time-consuming and tedious sampling procedure, it was observed that SPE LiChrolut EN , revealed to be the most effective technique allowing the extraction of a higher number of compounds (78) rather than the other extraction techniques studied.

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Section: Hs-spme Analysismentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Effectiveness of high-throughput miniaturized sorbent- and solid phase microextraction techniques combined with gas chromatography–mass spectrometry analysis for a rapid screening of volatile and semi-volatile composition of wines—A comparative study

Mendes¹,

Gonçalves²,

Câmara³

2012

Talanta

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“…Researching the drug transfer process in this novel device is necessary for supporting the control method for cell pulse dosing. It is known that the mass transfer between deionized water droplets and continuous phases octanol can be observed that there is a vortex on the surface of the microdroplets [24] and the solute transfer at the instantaneous two-phase interface is proportional to the square of the time [25]. The drug diffusion to cells through microporous membrane from microdroplet surround by oil is influenced by these factors, especially the mechanism of mass transfer through membrane in fluid.…”

Section: Introductionmentioning

confidence: 99%

Effects of Pulse Interval and Dosing Flux on Cells Varying the Relative Velocity of Micro Droplets and Culture Solution

et al. 2018

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Microdroplet dosing to cell on a chip could meet the demand of narrow diffusion distance, controllable pulse dosing and less impact to cells. In this work, we studied the diffusion process of microdroplet cell pulse dosing in the three-layer sandwich structure of PDMS (polydimethylsiloxane)/PCTE (polycarbonate) microporous membrane/PDMS chip. The mathematical model is established to solve the diffusion process and the process of rhodamine transfer to micro-traps is simulated. The rhodamine mass fraction distribution, pressure field and velocity field around the microdroplet and cell surfaces are analyzed for further study of interdiffusion and convective diffusion effect. The cell pulse dosing time and drug delivery efficiency could be controlled by adjusting microdroplet and culture solution velocity without impairing cells at micro-traps. Furthermore, the accuracy and controllability of the cell dosing pulse time and maximum drug mass fraction on cell surfaces are achieved and the drug effect on cells could be analyzed more precisely especially for neuron cell dosing.

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“…There are as many as 1018 kinds of ionic liquids available in literature [16]. Recently, room temperature ionic liquids with unique properties such as negligible vapour pressure, water stability, favourable viscosity and density characteristics, good thermal stability, non-volatility and good selective solubility have been used as alternative solvents separation purposes [17,18].…”

Section: Introductionmentioning

confidence: 99%

Separation and Determination of Cadmium(II) in Wastewater by Bisolvent of Ester and Ionic Liquid Flotation System

Hou¹,

Li²,

Zhao³

2018

Asian J. Chem.

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In this study, the flotation technology was used to separate and enrich the heavy metal Cd 2+ ions. Based on literature, it was found that Cd 2+ could form CdI4 2-with KI in solution and then (RhB)2(CdI4) was occurred when CdI4 2-was mixed with rhodamine B. This ternary associate was determined by bisolvent of ester and ionic liquid flotation system. Ionic liquid was [Bmim]BF4, the optimal amount of acetic acid, potassium iodide and rhodamine B was 8, 20 and 4 mL, respectively. The best removal efficiency obtained at a flotation time of 15 min with air flow rate of 30 mL/min and 38 % mass fraction of (NH4)2SO4 solution was 95.68 %. The experimental data indicated that the ionic liquid have more excellent function than the traditional organic solvents.

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Critical review on recent developments in solventless techniques for extraction of analytes

Cited by 258 publications

References 270 publications

Effectiveness of high-throughput miniaturized sorbent- and solid phase microextraction techniques combined with gas chromatography–mass spectrometry analysis for a rapid screening of volatile and semi-volatile composition of wines—A comparative study

Effectiveness of high-throughput miniaturized sorbent- and solid phase microextraction techniques combined with gas chromatography–mass spectrometry analysis for a rapid screening of volatile and semi-volatile composition of wines—A comparative study

Effects of Pulse Interval and Dosing Flux on Cells Varying the Relative Velocity of Micro Droplets and Culture Solution

Separation and Determination of Cadmium(II) in Wastewater by Bisolvent of Ester and Ionic Liquid Flotation System

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