The chirality in thallium isotopes is investigated by using adiabatic and configuration-fixed constrained triaxial relativistic mean field theory. Several minima with prominent triaxial deformation and proper configuration, where the chiral doublet bands are possible to appear, are obtained in odd-odd nuclei $^{192,194,196,198}$Tl and odd-mass nuclei $^{193,195,197}$Tl. Furthermore, the possible existence of multiple chiral doublet bands (M$\chi$D) is demonstrated in $^{192,193,194,195,196,197,198}$Tl. As chiral doublet bands in $^{193,194,198}$Tl and M$\chi$D in $^{195}$Tl have been observed in experiment, further experimental explorations for the chirality in $^{192,196,197}$Tl and M$\chi$D in thallium isotopes are expected to verify the predictions.