Critical iron deficiency anemia with record low hemoglobin: a case report

Chai, Audrey L.; Huang, O.; Rakocevic, Rastko; Chung, Peter

doi:10.1186/s13256-021-03024-9

Cited by 14 publications

(14 citation statements)

References 8 publications

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“…Therefore, it is necessary to appropriately identify and treat high-risk patients with severe anemia. All three patients in the present study had a background of not seeking appropriate medical attention, which is in agreement with the existing literature (9,11,12). The cases of a socially vulnerable 42-year-old woman with a hemoglobin level of 1.4 g/dl (9), of a 21-year-old woman with mental retardation and a hemoglobin level of 1.7 g/dl (11) and of a 29-year-old woman with celiac disease and anorexia nervosa showing a hemoglobin level of 1.7 g/dl (12) were reported in 2021, 2013 and 2005, respectively.…”

Section: Discussionsupporting

confidence: 92%

“…Cases of severe iron deficiency anemia complicated with uterine fibroids are not rare. However, only one case of severe anemia due to uterine fibroids with hemoglobin levels <2.0 g/dl has been reported to date (9). The present study reported three cases of life-threatening anemia with hemoglobin levels <2.0 g/dl caused by uterine fibroids and genital bleeding.…”

Section: Introductioncontrasting

confidence: 41%

“…The present report is the largest case series showing a detailed clinical course of patients with life-threatening anemia (hemoglobin levels <2.0 g/dl) caused by uterine fibroids. To date, only three cases of severe anemia with hemoglobin levels <2.0 g/dl have been reported (9,11,12). The present study summarized these and its own three cases in Table II.…”

Section: Discussionmentioning

confidence: 79%

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Life-threatening anemia due to uterine fibroids: A case series

et al. 2022

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Uterine fibroids are associated with heavy menstrual bleeding, abdominal discomfort, subfertility and a reduced quality of life. The present study reported a case series of life-threatening anemia with hemoglobin levels <2.0 g/dl caused by uterine fibroids and genital bleeding. Case 1 was of a 34-year-old woman who was transported to the emergency department of the Department of Obstetrics and Gynecology, Faculty of Medicine, Oita University because of a decline in consciousness level. She had been experiencing excessive and prolonged menstruation for many years but had not sought medical help. A 5-cm uterine submucosal leiomyoma was detected and the patient underwent hysteroscopic myomectomy. Case 2 was of a 36-year-old woman with a history of blood transfusions owing to severe anemia who was presented with progressive dyspnea. Although it was repeatedly explained her that her condition was life threatening, she refused to be hospitalized. Her hemoglobin level was 1.7 g/dl. Multiple uterine fibroids and adenomyosis were detected and total hysterectomy was performed. Case 3 was of a 49-yearold woman who was transported to the emergency department of the Department of Obstetrics and Gynecology, Faculty of Medicine, Oita University due to abdominal pain and severe anemia. Blood testing revealed a hemoglobin level of 1.9 g/dl. Multiple uterine fibroids with a maximum diameter of 8.5 cm were detected. However, the patient insisted on discharge because of lack of disease awareness. Total hysterectomy was performed. The present study is the largest case series showing a detailed clinical course of patients with life-threatening anemia with hemoglobin levels <2.0 g/dl. Additionally, Case 1 of the present series exhibited the lowest hemoglobin level (1.1 g/dl) reported to date. The present cases and a review of the literature suggested that the most important risk factors of life-threatening anemia are the patient's mental, social and personal factors, rather than the organic and functional abnormalities of the uterus.

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Section: Discussionsupporting

confidence: 92%

Section: Introductioncontrasting

confidence: 41%

Section: Discussionmentioning

confidence: 79%

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Life-threatening anemia due to uterine fibroids: A case series

et al. 2022

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“…A 45-year-old woman had an even lower hemoglobin level of 1.4 g/dL. Like our case, she was diagnosed with leiomyomas; however, she was unable to walk, with a history of a mechanical fall [ 14 ]. Another middle-aged woman with celiac disease complained of stomach discomfort and exhaustion [ 15 ].…”

Section: Discussionmentioning

confidence: 98%

Iron Deficiency Anemia With a Life-Threatening Low Hemoglobin Level

Alateeq¹,

Alshammari²,

Alsaif³

2021

Cureus

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Iron deficiency anemia (IDA) accounts for roughly half of all anemia cases globally. Menorrhagia and menstrual cycle disorders render women of childbearing age more prone to IDA. One of the leading causes of menorrhagia is uterine fibroids (leiomyomas), which are defined as hyperplastic, usually benign, overgrowths of uterine wall muscle and connective tissue. This is a case report of a 45-year-old woman who came to the emergency department complaining of progressive fatigue and dizziness for two months. She was admitted as a case of life-threatening IDA with a hemoglobin level of 3.0 g/dL. She was ambulatory and hemodynamically stable without any features of severe anemia. Pelvic ultrasound was performed and revealed uterine fibroids. After partial correction of the anemia, she underwent a total hysterectomy as a definitive treatment.

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“…There are other cases reporting critically low hemoglobin associated with AUB, but none of these patients had pancytopenia. A case of a 42-year-old woman with menorrhagia was reported with a hemoglobin of 1.4 g/dL but she was symptomatic with anemia, experiencing dizziness, fatigue and shortness of breath, and had normal platelet and white cell counts [ 9 ]. A case of a 21-year-old with AUB and a hemoglobin of 1.7g/dL was reported, but this patient was hemodynamically unstable with hypotension and tachycardia, and no associated pancytopenia [ 10 ].…”

Section: Discussionmentioning

confidence: 99%