Critical evaluation of biochemical and imaging diagnostic assessment in primary hyperparathyroidism

Gibb, Fraser; Muthukrishnan, Bala; Reid, Lesley Williams

doi:10.1530/endoabs.50.p053

Cited by 1 publication

(1 citation statement)

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“…Although a gold-standard modality is required, early experience with parathyroid scintigraphy may indicate parathyroid adenoma. 4 In our case, iPTH, and calcium levels were high, creatinine clearance was low and parathyroid scintigraphy was suggestive of an adenoma.…”

Section: Discussionmentioning

confidence: 45%

A Young Man with a Palpable Parathyroid Tumor Presented by Renal Colic

Türe

Demirci

Türkmen

2018

Turkish Journal of Family Medicine and Primary Care

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Objective(s):Primary hyperparathyroidism (PH) is characterized by a high level of blood PTH and calcium. Case: A 23-year-old male patient with no previous history of any chronic disease was referred to the urology polyclinic of the hospital due to renal colic. On the direct urinary system chart and in the urinary system ultrasonography, left ureter calculi and grade-2 hydronephrosis were detected in the left kidney. The patient's serum calcium and ionized parathyroid tests were determined to be high and he was consulted to an internist with a prediagnosis of primary hyperparathyroidism. Thyroid / Parathyroid Ultrasonography showed a 12 * 13 * 23-millimeter size, well-defined hypoechoic, slightly heterogeneous solid lesion in the left parathyroid root. Parathyroid scintigraphy sestamibi technetium-99 detected a parathyroid adenoma/hyperplasia in the posterior vicinity of the middle part of the left lobe of the thyroid. Discussion: In a young patient, a neck mass usually originates from a congenital disease or due to acute infection. Parathyroid tumors are rare causes of neck masses at young ages. However, physicians should pay attention to additional findings associated with conditions that may be more serious than the presenting symptoms. In this case, it was a parathyroid tumor diagnosed by careful physical examination of a patient with renal colic. ÖZETHastalığı olmayan 23 yaşındaki erkek hasta renal kolik nedeniyle hastanenin üroloji polikliniğine başvurdu. Hastada serum kalsiyum ve iyonize parathormon sonuçları yüksekti ve hasta bu sonuçlarla primer hiperparatiroidizm ön tanısı ile iç hastalıkları uzmanına konsülte edildi. Hastanın Tiroid / Paratiroid Ultrasonografi incelemesinde: sol paratiroid kökünde 12 * 13 * 23 milimetre boyutlarında, iyi tanımlanmış, hipoekoik, hafif heterojen solid lezyona rastlandı. Paratiroid sintigrafi sestamibi teknisyum-99 incelemesinde tiroidin sol lobu orta kısım arka komşuluğunda bir paratiroid adenomu/hiperplazisi tespit edildi. Tartışma: Aile hekimleri günlük pratiklerine boyun kitleleri ile sıklıkla karşılaşırlar. Genç erişkinlerde boyun kitlelerinin en sık nedenleri konjenital hastalıklar veya enfeksiyonlardır. Paratiroid patolojileri boyun kitleleri genç yaşta nadirdir. Sonuç: Genç bir hastada, boyun kitlesi bir konjenital hastalık veya akut bir enfeksiyona bağlıdır. Bununla beraber, hekimler hastanın mevcut semptomlarından çok daha ciddi durumların işareti olan bulgulara dikkat etmelidir. Bu vakada renal kolik şikayeti ile başvuran bir hastada dikkatli bir muayene ile ortaya konulan bir paratiroid adenomu sunulmuştur.

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Section: Discussionmentioning

confidence: 45%