Critical care in uraemic children

Leititis, J. U.; Brandis, M.

doi:10.1007/bf00856850

Cited by 3 publications

(1 citation statement)

References 78 publications

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“…However, the timing of the initiation and cessation of RRT has been a subject of long-standing debate. In resource-limited facilities where RRT via extracorporeal circuit is not available, peritoneal dialysis can be considered as an alternative mode of RRT [35][36]. Novel extracorporeal therapies using similar devices but employing the mechanism of adsorption have been developed and extensively studied in recent decades.…”

Section: Renal Replacement Therapy and Extracorporeal Blood Pu-rifica...mentioning

confidence: 99%

A Thai guideline summary in management of pediatric septic shock

Samransamruajkit,

Saelim,

Uppala

et al. 2024

Clin Crit Care

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Sepsis-associated organ dysfunction, particularly septic shock, is a prevalent critical illness characterized by increased morbidity and mortality, particularly in children. Recognizing the imperative to enhance outcomes, a septic shock guideline tailored for pediatric patients was formulated. This guideline strives to establish an evidence-based framework for the effective management of septic shock and sepsis-associated organ dysfunction in Thai children. Key components encompass the prompt identification and stabilization of patients, meticulous titration of fluids and vasoactive agents, initiation of empirical antimicrobial therapy, judicious infectious source control, respiratory support, administration of sedation and analgesia, blood and blood product transfusion, correction of electrolyte imbalances, management of metabolic derangements, renal replacement therapy, and the implementation of multimodal monitoring. The objective is to optimize management, achieving therapeutic goals while continuously reassessing the patient's condition. Additionally, this guideline demonstrates adaptability by tailoring its suggestions to the resources available in Thailand’s medical facilities. Recognizing the diverse capabilities of healthcare institutions, the guideline endeavors to ensure its implementation is practical and feasible.

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Section: Renal Replacement Therapy and Extracorporeal Blood Pu-rifica...mentioning

confidence: 99%

A Thai guideline summary in management of pediatric septic shock

Samransamruajkit,

Saelim,

Uppala

et al. 2024

Clin Crit Care

View full text Add to dashboard Cite

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Hemostatic complications in renal disorders of the young

Andrew

Brooker

1996

Pediatr Nephrol

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This review focuses on the hemorrhagic and thrombotic complications sometimes associated with the most common renal disorders in children. A Medline search of the literature was conducted from 1966 to January 1995, using combinations of key words appropriate for each disorder. Additional references were located through the bibliographies of the publications and recent journals were searched independently. The most common renal disorders with hemostatic complications in children were: renal vein thrombosis (268 children in 80 publications), hemolytic uremic syndrome (473 children in 29 publications), nephrotic syndrome (4,158 children in 51 publications), renal transplantation (3,976 children in 14 publications), glomerulonephritis (20 publications), end-stage renal disease, and dialysis (22 publications). The age distribution, clinical presentation, etiology, diagnosis, treatment, and outcome of the affected children were analyzed for each disorder. Children with inherited pre-thrombotic disorders usually do not present during childhood unless there is a secondary risk factor. Similarly, most children with renal disease do not develop thromboembolic complications. Therefore, when a child with a renal disorder develops a thromboembolic event, evaluation for an inherited pre-thrombotic disorder should be seriously considered. Guidelines for the use of heparin and warfarin in these children (both therapeutically and prophylactically) are given. At this time, the risk/benefit of thrombolytic therapy in children is not known and a general recommendation for thrombolytic therapy cannot be made.

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