Critical assessment of smear-positive pulmonary tuberculosis patients after chemotherapy under the district tuberculosis programme

Datta, Manjula; Radhamani, M P; Selvaraj, Raja; Paramasivan, C. N.; Gopalan, B N; Sudeendra, C.R.; Prabhakar, R

doi:10.1016/0962-8479(93)90008-l

Cited by 68 publications

(36 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The most probable reason for this seems to be improper application of diagnostic and treatment techniques under the National Tuberculosis Programme (NTP) over the last four decades. Its performance in terms of case finding and treatment has been below expectation (Datta et al 1993;Suryanarayana et al 1995;NTI Bangalore 2001). This has special relevance to tribal areas considering the difficult terrain resulting in irregular drug supply and poor supervision by programme officials.…”

Section: Discussionmentioning

confidence: 99%

Annual risk of tuberculosis infection among tribal population of central India

Rao

Gopi

Yadav

et al. 2008

Tropical Med Int Health

View full text Add to dashboard Cite

Summaryobjective To estimate the annual risk of tuberculosis infection (ARTI) among tribal children of Madhya Pradesh, central India.methods Community-based, cross-sectional tuberculin survey among children aged 1-9 years in the tribal population of Madhya Pradesh. Multistage stratified cluster sampling was used to select a representative random sample of villages predominated by tribal population from selected districts. A total of 4802 children were tuberculin-tested with 1TU of PPD RT 23 and the reaction sizes read after 72 h.results A total of 3062 (64%) children had no BCG scar. The frequency distribution of children by reaction sizes indicated a fair mode at 18 mm in the right hand side of the distribution. By mirror-image technique, the prevalence of infection among children with no recognizable BCG scar was estimated as 6.8% (95% CI: 4.8-8.9%). The ARTI was computed as 1.3% (0.9-1.7%). The corresponding figures for children irrespective of scar status were 7.1% (95% CI: 5.5-8.8%) and 1.3% (1.0-1.7%) respectively.

show abstract

Section: Discussionmentioning

confidence: 99%

Annual risk of tuberculosis infection among tribal population of central India

Rao

Gopi

Yadav

et al. 2008

Tropical Med Int Health

View full text Add to dashboard Cite

show abstract

“…A survey conducted in the city of Santa Cruz suggested that prescribing incorrect anti-TB treatments was not infrequent among private physicians (15). Medical practice that ignores appropriate treatment norms may have dire consequences for patients and the community (16).…”

Section: Discussionmentioning

confidence: 99%

Patients with tuberculosis in Bolivia: why do they die?

Ollé-Goig¹

2000

Rev Panam Salud Publica

View full text Add to dashboard Cite

“…However, casetfatality rates among TB patients reported in the literature range from 12% to 44% and are not comparable because they were measured as cumulative incidence for different followtup periods. [2][3][4][5][6][7][8] Risk factors such as smoking, alcoholism, irregular and incomplete antittuberculosis treatment as well as HIV infection are known to increase the mortality associated with TB. 2,4,5,7,9 WHO defines TB mortality as the number of TB cases dying during treatt t ment, regardless of the cause.…”

Section: Introductionmentioning

confidence: 99%

Mortality and tuberculosis patients in Chennai, India

Kolappan

Subramani

Karunakaran

et al. 2006

Bull World Health Organ

View full text Add to dashboard Cite

Objective We aimed to measure the mortality rate and excess general mortality as well as identify groups at high risk for mortality among a cohort of tuberculosis patients treated in Chennai Corporation clinics in south India. Methods In this retrospective cohort study we followed up 2674 patients (1800 males and 874 females) who were registered and treated under the DOTS strategy in Chennai Corporation clinics in 2000. The follow-up period from the date of start of treatment to either the date of interview, or death was 600 days. Findings The mortality rate among this cohort of tuberculosis patients was 60/1000 person-years. The excess general mortality expressed as standardized mortality ratio (SMR) was 6.1 (95% confidence interval (CI) = 5.4-6.9). Younger patients, men, patients with Category II disease, patients who defaulted on, or failed courses of treatment, and male smokers who were alcoholics, all had higher mortality ratios when compared to the rest of the cohort. Conclusion The excess mortality in this cohort was six times more than that in the general population. Young age, male sex, smearpositivity, treatment default, treatment failure and the combination of smoking and alcoholism were identified as risk factors for tuberculosis mortality. We suggest that mortality rate and excess mortality be routinely used as a monitoring tool for evaluating the efficiency of the national control programme.Bulletin of the World Health Organization 2006;84:555-560.Voir page 559 le résumé en français. En la página 560 figura un resumen en español. IntroductionTuberculosis (TB) is a major public health problem in India and most of the disease burden is due to premature mort t tality among TB patients.1 Mortality is measured either as true rate (personttime rate) or as risk of death within a specific time period of followtup (casetfatality rate). The casetfatality rate is the more commonly used mortality measure of the two. However, casetfatality rates among TB patients reported in the literature range from 12% to 44% and are not comparable because they were measured as cumulative incidence for different followtup periods.2-8 Risk factors such as smoking, alcoholism, irregular and incomplete antittuberculosis treatment as well as HIV infection are known to increase the mortality associated with TB. 2,4,5,7,9 WHO defines TB mortality as the number of TB cases dying during treatt t ment, regardless of the cause.10 This definition, however, does not reflect the actual TB mortality rate because it includes deaths due to cotmorbidities and accidents, excludes deaths among treatment defaulters who have a high risk for mortality and presupposes that TB mortality does not occur after the completion of treatment. A better, though indirect, measure of mortality would be the computation of excess mortality (or standardized mortality ratio (SMR)) occurring among TB pat t tients and comparing it to the mortalt t ity among the standard population (or the estimated national population for a certain year). Since 1999, the Chennai Cor...

show abstract

Critical assessment of smear-positive pulmonary tuberculosis patients after chemotherapy under the district tuberculosis programme

Cited by 68 publications

References 5 publications

Annual risk of tuberculosis infection among tribal population of central India

Annual risk of tuberculosis infection among tribal population of central India

Patients with tuberculosis in Bolivia: why do they die?

Mortality and tuberculosis patients in Chennai, India

Contact Info

Product

Resources

About