2014
DOI: 10.1089/vbz.2013.1364
|View full text |Cite
|
Sign up to set email alerts
|

Criteria for Identifying and Evaluating Candidate Sites for Open-Field Trials of Genetically Engineered Mosquitoes

Abstract: Recent laboratory successes in the development of genetically engineered mosquitoes for controlling pathogen transmission have fostered the need for standardized procedures for advancing the technical achievements to practical tools. It is incumbent in many cases for the same scientists doing the in-laboratory discovery research to also take on the initial challenges of developing the pathway that will move the technologies to the field. One of these challenges is having a set of criteria for selecting collabo… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1
1

Citation Types

1
33
0

Year Published

2015
2015
2023
2023

Publication Types

Select...
6
4

Relationship

2
8

Authors

Journals

citations
Cited by 36 publications
(34 citation statements)
references
References 40 publications
(47 reference statements)
1
33
0
Order By: Relevance
“…Effector gene stability in different genetic backgrounds and under diverse environmental conditions and efficacy against genetically diverse parasites need further research to ensure that the constructs function as well in the field as they do in the laboratory. In addition, significant advances in regulatory structures and ethical models of community engagement are as important as the further scientific development of these technologies (7,42,43). It is incumbent on the scientist developing these technologies to interact openly and freely with the potential end users.…”
Section: Discussionmentioning
confidence: 99%
“…Effector gene stability in different genetic backgrounds and under diverse environmental conditions and efficacy against genetically diverse parasites need further research to ensure that the constructs function as well in the field as they do in the laboratory. In addition, significant advances in regulatory structures and ethical models of community engagement are as important as the further scientific development of these technologies (7,42,43). It is incumbent on the scientist developing these technologies to interact openly and freely with the potential end users.…”
Section: Discussionmentioning
confidence: 99%
“…Additionally, implicit in the optimal spatial release of sterile insects is the necessity of estimating the carrying capacity for the wild populations in the natural environment and the associated spatial movement through dispersal ability Brown et al, 2014), among other relevant features. Indeed, one of the critical parameters for SIT deployment is to find threshold values for the population density that determine the appropriate time to treat and the number of sterilized males that must be released to achieve a desired goal (Jeffery et al, 2009).…”
Section: Introductionmentioning
confidence: 99%
“…Technical guidance is only part of the picture. There is a critical need for guidance on best practices for community engagement, consolidating and expanding lessons learned from the case studies to date 911 .…”
Section: To the Editormentioning
confidence: 99%