CRISPR Screen Reveals PACT as a Pro-Viral Factor for Dengue Viral Replication
Shwetha Shivaprasad,
Wenjie Qiao,
Kuo-Feng Weng
et al.
Abstract:The dengue virus is a single-stranded, positive-sense RNA virus that infects ~400 million people worldwide. Currently, there are no approved antivirals available. CRISPR-based screening methods have greatly accelerated the discovery of host factors that are essential for DENV infection and that can be targeted in host-directed antiviral interventions. In the present study, we performed a focused CRISPR (Clustered Regularly Interspaced Palindromic Repeats) library screen to discover the key host factors that ar… Show more
It is with great enthusiasm that we introduce the third edition of the “Virus–Host Interaction” series, a collection that epitomizes the ever-evolving landscape of virology [...]
It is with great enthusiasm that we introduce the third edition of the “Virus–Host Interaction” series, a collection that epitomizes the ever-evolving landscape of virology [...]
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