CRISPR and Artificial intelligence to improve precision medicine: Future Perspectives and Potential Limitations

Abstract

The CRISPR/Cas9 genome editing system is a unique and new technology that allows genetics and medical researchers to modify or edit parts of the genome. This is done by deleting, inserting or changing parts of the DNA sequence. This method is currently the simplest, most widely used, and the most accurate method of genetic manipulation. This system has great potential to treat a wide range of genetic diseases. However, more research is needed to determine the advantages and disadvantages of the CRISPR system and establish best practices. On the other hand, individual patient treatment is one of the main goals of the medical field. Achieving this goal has been elusive due to a complex set of factors affecting disease and health. This work highlights key advances in the development of enabling technologies that advance the goal of personalized and precision medicine. Artificial intelligence is a simulation of human intelligence for computers, and is used in the interface of machines that is programmed to think and behave like a human. This review summarizes recent developments in the artificial intelligence (AI), CRISPR/Cas9, and examining clinical trials and potential based on these two in the advancement and development of precision and personalized medicine, cancer treatment and current and future challenges. Finally, the application of (AI) in the modification of the CRISPR/Cas9 system is highlighted.