Crinum jagus (J. Thomps. Dandy): Antioxidant and protective properties as a medicinal plant on toluene-induced oxidative stress damages in liver and kidney of rats

Prefeeding of Clarias gariepinus with Spirulina platensis counteracts petroleum hydrocarbons-induced hepato- and nephrotoxicity

“…The histopathological abnormalities in the liver and kidney of exposed groups are in the same line with those reported in the studies of Sayed et al 7 , 8 . As a consequence of loss of antioxidant defensive shield to fight damaging free radicals and increase in death-mediated proteoses 52 , 53 , and following the observations of Sayed et al 7 , 54 , our results revealed presence of necrotic alterations in the liver of benzene group and epithelial sloughing in the kidney of benzene and toluene groups. Loss of hepatocellular integrity is associated with the release of its metabolizing enzymes into the bloodstream 40 .…”

RETRACTED: Ephedra alata subsp. alenda (Ephedraceae) leaf extracts: phytochemical screening, anti-diabetic, anti-obesity and anti-toxic activities on diabetic-induced liver-kidney-testes toxicities and inhibition of α-amylase and lipase enzymes

“…finally, liver, kidney and testes organ were sectioned into 5 μm-thick histological sections. Liver, kidney and testes sections were stained with hematoxylin and eosin solution (H &E), and photographed by a Olympus CX41 light microscope [ 18 ].…”

“…Medicinal plants have always been important in many fields worldwide and contain certain contain various types of bioactive compounds with multiple therapeutics effects. In fact, plant phenolics drugs have been used for the treatment and prevention of multiple human diseases including diabetes, cancer, hypertension, and others [ [12] , [13] , [14] , [15] , [16] , [17] , [18] ]. Ephedra alata was an important source of various bio-actives drugs such glycosides, flavonoids, phenolic compounds, and alkaloids.…”

“…Ephedra alata was an important source of various bio-actives drugs such glycosides, flavonoids, phenolic compounds, and alkaloids. Previous studies reported have reported that this plant exert identical biological activities as antibacterial, liver function protection, prevention of cardiovascular diseases, and prevention and amelioration of cancer [ [17] , [18] , [19] , [20] , [21] , [22] , [23] , [24] , [25] ]. A number of natural products possess the ability to prevent obesity by digestive enzymes as lipase and α-amylase [ 6 , [26] , [27] , [28] ].…”

A Quantitative Study of Inappropriate Image Duplication in the JournalToxicology Reports

“…One false positive was previously identified by an author responding on PubPeer, and this example was removed from the dataset prior to analysis. The risk of false positives and difficulties in determining the true number of duplications should not discourage research into scientific misconduct, encouragingly, three corrigenda have been published by Toxicology Reports which were initiated by the authors after corresponding comments were posted to PubPeer 6–8 . Alternative approaches, for example generating synthetic datasets containing manipulated images will likely prove useful to benchmark the performance of automated tools 9 .…”