Creutzfeldt–Jakob disease and ENT

Abstract

This is a controversial area in medicine, and ENT in particular. This review highlights a clinically applicable approach for everyday use.

Shaken, Not Sonicated?

“…4 In contrast, detection of low amounts of abnormal PrP seeds in the urine of patients with variant Creutzfeldt-Jakob disease caused by exposure to bovine spongiform encephalopathy (and not in the urine of patients with other forms of Creutzfeldt-Jakob disease) confirms the widespread dispersal of the variant Creutzfeldt-Jakob disease prion throughout the body. There is no epidemiologic evidence of nasal or aerosolborne transmission of sporadic Creutzfeldt-Jakob disease, but Orrú et al point to recent evidence that these pathways are highly effective in experimental models.…”

Days of change at the JLO

“…At present, we continue to publish about one-third of the material submitted to The Journal . We are particularly pleased with some of the high-quality review articles that we have been able to commission, as these articles reflect the latest opinion in the field of otolaryngology, and hopefully are of wide appeal 1 – 4 . The sourcing of high-quality review articles has been assisted by one of our Editorial Board, Vin Paleri.…”

Focus on the external auditory canal

“…This disease has fluctuated in prominence in the public eye and is reviewed by Sethi and colleagues. 4 In the past, precautions to minimise the transmission of CJD have lacked an evidence base. This review gathers together all current evidence in order to propose simple precautions which can be introduced into everyday practice.…”

“…Another area of controversy concerning the potential transmission of infective material is that of Creutzfeldt–Jakob disease (CJD). This disease has fluctuated in prominence in the public eye and is reviewed by Sethi and colleagues 4 . In the past, precautions to minimise the transmission of CJD have lacked an evidence base.…”