Creep behavior of the intact and meniscectomy knee joints

Kazemi, Maryam; Li, L.P.; Savard, P.; Buschmann, Michael D.

doi:10.1016/j.jmbbm.2011.05.004

Cited by 63 publications

(54 citation statements)

References 45 publications

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“…This higher impressed current density on the medial side is consistent with higher hydrostatic pressures in the medial compartment compared to the lateral compartment of the joint [39], [43], and by the relationship between the magnitude of the streaming potentials and the pressure gradient [40].…”

Section: Discussionsupporting

confidence: 68%

“…To understand its mechanical behavior under loading, the cartilage has been modeled as a biphasic linear medium [16], a poroviscoelastic medium [35], or a medium reinforced with collagen fibrils [36]. Given the complexity of realistic geometry and the governing differential equations, FEMs have often been used to investigate cartilage inhomogeneity [37], the presence of chondrocytes [38], or the effects of meniscectomy [39]. The electromechanical behavior of cartilage and the generation of streaming potentials have also been investigated with an electrokinetic model relating fluid flow and electrical current density to the pressure and electrical potential gradients [40], [41].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

The Forward Problem of Electroarthrography: Modeling Load-Induced Electrical Potentials at the Surface of the Knee

Han

Buschmann

Savard

2014

IEEE Trans. Biomed. Eng.

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Electroarthrography (EAG) is a novel technology recently proposed to detect cartilage degradation. EAG consists of recording electrical potentials on the knee surface while the joint is undergoing compressive loading. Previous results show that these signals originating from streaming potentials in the cartilage reflect joint cartilage health. The aim of this study is to contribute to the understanding of the generation of the EAG signals and to the development of interpretation criteria using computer models of the human knee. The knee is modeled as a volume conductor composed of different regions characterized by specific electrical conductivities. The source of the EAG signal is the load-induced interstitial fluid flow that transports ions within the compressed cartilage. It is modeled as an impressed current density in different sections of the articular cartilage. The finite-element method is used to compute the potential distribution in two knee models with a realistic geometry. The simulated potential distributions correlate very well with previously measured potential values, which further supports the hypothesis that the EAG signals originate from compressed cartilage. Also, different localized cartilage defects simulated as a reduced impressed current density produce specific potential distributions that may be used to detect and localize cartilage degradation. In conclusion, given the structural and electrophysiological complexity of the knee, computer modeling constitutes an important tool to improve our understanding of the generation of EAG signals and of the various factors that affect the EAG signals so as to help develop the EAG technology as a useful clinical tool.

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Section: Discussionsupporting

confidence: 68%

Section: Discussionmentioning

confidence: 99%

The Forward Problem of Electroarthrography: Modeling Load-Induced Electrical Potentials at the Surface of the Knee

Han

Buschmann

Savard

2014

IEEE Trans. Biomed. Eng.

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“…After meniscus surgery patients are at high risk for knee osteoarthritis [22], which is partly thought to result from compromised ability to absorb and distribute the load across the joint [3,17]. Our findings provide no evidence to support a relationship between knee muscle strength assessed 3 months after arthroscopic partial meniscectomy and 2-year change in knee adduction moment parameters.…”

Section: Discussioncontrasting

confidence: 61%

Knee Muscle Strength After Recent Partial Meniscectomy Does Not Relate to 2-year Change in Knee Adduction Moment

Hall

Wrigley

Metcalf

et al. 2014

Clinical Orthopaedics &Amp; Related Research

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“…In particular, collagen fibrils have been shown to have a significant role in distributing stresses, strains and pore pressures during impact or dynamic loading of the knee joint Korhonen et al 2003;Krishnan et al 2003;Federico and Herzog 2008;Julkunen et al 2008;Li et al 2009;Pierce et al 2010Pierce et al , 2012Mononen et al 2011Mononen et al , 2012. However, the previous models of knee joints with fibril-reinforced cartilage materials, including depthdependent collagen fibril architecture and split-line orientations, have not included a gait cycle loading (Shirazi and Shirazi-Adl 2009;Gu and Li 2011;Kazemi et al 2011;Mononen et al 2012). Furthermore, the medial -lateral translations have not been considered in any of the previous FE studies (Yang et al 2010;Netravali et al 2011;Saveh et al 2011), and varus -valgus rotation of the models has not been compared with experimental data (Netravali et al 2011).…”

Section: Introductionmentioning

confidence: 99%

Implementation of a gait cycle loading into healthy and meniscectomised knee joint models with fibril-reinforced articular cartilage

Mononen¹,

Jurvelin²,

Korhonen³

2013

Computer Methods in Biomechanics and Biomedical Engineering

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Computational models can be used to evaluate the functional properties of knee joints and possible risk locations within joints. Current models with fibril-reinforced cartilage layers do not provide information about realistic human movement during walking. This study aimed to evaluate stresses and strains within a knee joint by implementing load data from a gait cycle in healthy and meniscectomised knee joint models with fibril-reinforced cartilages. A 3D finite element model of a knee joint with cartilages and menisci was created from magnetic resonance images. The gait cycle data from varying joint rotations, translations and axial forces were taken from experimental studies and implemented into the model. Cartilage layers were modelled as a fibril-reinforced poroviscoelastic material with the menisci considered as a transversely isotropic elastic material. In the normal knee joint model, relatively high maximum principal stresses were specifically predicted to occur in the medial condyle of the knee joint during the loading response. Bilateral meniscectomy increased stresses, strains and fluid pressures in cartilage on the lateral side, especially during the first 50% of the stance phase of the gait cycle. During the entire stance phase, the superficial collagen fibrils modulated stresses of cartilage, especially in the medial tibial cartilage. The present computational model with a gait cycle and fibril-reinforced biphasic cartilage revealed time- and location-dependent differences in stresses, strains and fluid pressures occurring in cartilage during walking. The lateral meniscus was observed to have a more significant role in distributing loads across the knee joint than the medial meniscus, suggesting that meniscectomy might initiate a post-traumatic process leading to osteoarthritis at the lateral compartment of the knee joint.

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Creep behavior of the intact and meniscectomy knee joints

Cited by 63 publications

References 45 publications

The Forward Problem of Electroarthrography: Modeling Load-Induced Electrical Potentials at the Surface of the Knee

The Forward Problem of Electroarthrography: Modeling Load-Induced Electrical Potentials at the Surface of the Knee

Knee Muscle Strength After Recent Partial Meniscectomy Does Not Relate to 2-year Change in Knee Adduction Moment

Implementation of a gait cycle loading into healthy and meniscectomised knee joint models with fibril-reinforced articular cartilage

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