This article presents a method for the analysis of test programs for informational interaction of technical systems with the command-and-software control. The study also deals with the creation of formal principles of the analysis of the structure and knowledge base of the intellectual simulation model, as well as it considers the tools for their infographic presentation. The new method is based on building and using digital twins combining the software-and-mathematical models of devices and knowledge bases describing the principles of their functioning and retrospective and operational data acquired during testing of the real equipment. The stages of the method implementation include the construction of digital twins of the function of the tested object, automated building of the knowledge base from the test programs, comparison of the constructed knowledge bases, simulation of environmental systems during autonomous tests and analysis of the informational interaction of the tested devices. The knowledge base is built on the basis of the parameters set in the test programs determining commands, ways of data transmission, tickets and actions of the onboard systems. The rules of the knowledge bases are simply interpreted, clear and they are described in terms of the subject area. The method provides the consideration of the existing variety of methods for the onboard equipment control performed on the basis of different approaches and communication protocols which can be set in the model during the onboard equipment design.