Creation and Validation of a Portuguese Version of the UCLA Scleroderma Clinical Trial Consortium Gastrointestinal Tract Instrument

Ferreira, Pedro Lopes; Genrinho, Inês; Santiago, Tânia; Carones, Adriana; Mazeda, Carolina; Barcelos, Anabela; Beirão, Tiago; Costa, Flávio; Santos, Inês; Couto, Maura; Rato, M.; Terroso, G.; Monteiro, Paulo P.

doi:10.3390/ijerph20021553

Cited by 2 publications

(2 citation statements)

References 29 publications

(51 reference statements)

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“…27 The UCLA-GIT 2.0 questionnaire is a recognized and reliable instrument to assess gastrointestinal (GI) symptoms in SSc patients and its impact on quality of life. 28 Recently validated to the Portuguese population 29 , it measures eight HRQoL dimensions (re ux, distention/bloating, fecal soilage, diarrhea, social functioning, emotional wellbeing, and constipation) and has been used in several clinical trials of GI treatments in patients with SSc as an outcome measure. 30,31 The total UCLA GIT score is calculated by averaging all the subscales, except the one for constipation, and ranges from 0 (best HRQoL) to 2.83 (worst HRQoL).…”

Section: It Assesses Eight Dimensions (Physical Functioning [Pf] Bodi...mentioning

confidence: 99%

Validation of the Portuguese version of the Scleroderma Health Assessment Questionnaire

Genrinho

Ferreira

Santiago

et al. 2023

Preprint

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Background The Health Assessment Questionnaire Disability Index (HAQ-DI) was completed with five visual analogue scales (VAS) to assess systemic sclerosis (SSc). These VAS address overall disease severity, Raynaud’s phenomenon, digital tip ulcers, gastrointestinal and lung symptoms. The new functional measurement instrument is called Scleroderma HAQ (SHAQ). It aims to perform a validation of the European Portuguese version of SHAQ for patients with SSc.Methods Patients with different forms of SSc from five Hospital Centres’ Rheumatology Departments were invited. The reliability of the Portuguese SHAQ was evaluated by internal consistency, using the Cronbach’s α, and by test-retest reliability, using the intraclass correlation coefficient (ICC). Construct validity was assessed by structural validity using factor analysis, and by known-groups hypotheses tests. Criterion validity was addressed by Pearson’s correlation with selected dimensions from the University of California Los Angeles Scleroderma Clinical Trial Consortium Gastrointestinal Tract Instrument (UCLA GIT 2.0), the Short Form Health Survey (SF-36v2), and the EuroQoL EQ-5D-5L.Results One hundred and two SSc patients agreed to participate, 31 of which answered to the retest. HAQ-DI demonstrated high internal consistency reliability (α=0.866) and the same measure and all five VAS also showed high test-retest reliability (ICC 0.61–0.95). In what concerns construct validity, we evidenced the unidimensionality of all VAS. HAQ-DI evidenced to be worse in males, patients older than 65 years and individuals with a diffuse form of SSc. Criterion validity was mainly evidenced through the correlation between HAQ-DI and SF-36v2 physical summary measure (r=-0.688) and EQ-5D-5L index score (r=-0.723). Likewise, SHAQ overall disease severity VAS was also correlated with SF-36v2 physical summary measure (r=-0.628). Because SHAQ is a functional disability measure, mental scores correlations were smaller. With the exception of Raynaud’s VAS, all the other VAS correlated well with similar clinical variables.Conclusion This paper provides evidence to demonstrate how reliable and valid the European Portuguese version of SHAQ is, to be used in SSc patients to assess the clinical severity under the perspective of patients.

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Section: It Assesses Eight Dimensions (Physical Functioning [Pf] Bodi...mentioning

confidence: 99%

Validation of the Portuguese version of the Scleroderma Health Assessment Questionnaire

Genrinho

Ferreira

Santiago

et al. 2023

Preprint

Self Cite

View full text Add to dashboard Cite

show abstract

“…Recently validated to the Portuguese population [30], it measures eight HRQoL dimensions (reflux, distention/bloating, fecal soilage, diarrhea, social functioning, emotional wellbeing, and constipation) and has been used in several clinical trials of GI treat-ments in patients with SSc as an outcome measure [31,32]. The total UCLA GIT score is calculated by averaging all the subscales, except the one for constipation, and ranges from 0 (best HRQoL) to 2.83 (worst HRQoL).…”

mentioning

confidence: 99%

Validation of the Portuguese Version of the Scleroderma Health Assessment Questionnaire

Genrinho,

Ferreira,

Santiago

et al. 2023

IJERPH

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The Health Assessment Questionnaire Disability Index (HAQ-DI) was completed with five visual analog scales to assess systemic sclerosis (SSc) called Scleroderma HAQ (SHAQ). We performed a validation of the European Portuguese version of SHAQ for patients with SSc. Patients with different forms of SSc from five Hospital Centers were invited. The reliability of the Portuguese SHAQ was evaluated by internal consistency and by test–retest reliability. Content validity was checked by two rheumatologists and by a panel of patients. Construct validity was assessed by structural validity and by known-groups hypothesis tests. Criterion validity was addressed with selected dimensions from the UCLA GIT 2.0, the SF-36v2, and the EuroQoL EQ-5D-5L. A total of 102 SSc patients agreed to participate, 31 of which answered to the retest. HAQ-DI demonstrated high internal consistency reliability (α = 0.866) and SHAQ also showed high test–retest reliability (ICC 0.61–0.95). We evidenced the unidimensionality of all VASs. HAQ-DI scores were worse in males, patients older than 65 years, and individuals with a diffuse form of SSc. Criterion validity was mainly evidenced through the correlation between the HAQ-DI and SF-36v2 physical summary measure (r = −0.688) and EQ-5D-5L index score (r = −0.723). Likewise, the SHAQ overall disease severity VAS was also correlated with SF-36v2 physical summary measure (r = −0.628). Mental score correlations were smaller. With the exception of the Raynaud’s VAS, all the other VASs correlated well with similar clinical variables. This paper provides evidence to demonstrate how reliable and valid the European Portuguese version of SHAQ is, to be used in SSc patients to assess the clinical severity under the perspective of patients.

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Creation and Validation of a Portuguese Version of the UCLA Scleroderma Clinical Trial Consortium Gastrointestinal Tract Instrument

Cited by 2 publications

References 29 publications

Validation of the Portuguese version of the Scleroderma Health Assessment Questionnaire

Validation of the Portuguese version of the Scleroderma Health Assessment Questionnaire

Validation of the Portuguese Version of the Scleroderma Health Assessment Questionnaire

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