Creatinin Excretion in Abnormal States Op Nutrition

The Urinary Excretion of Protein, Non-Protein Nitrogen, Creatinine and Uric Acid in Ageing Male Rats

“…It is generally held that the level of the excretion of creatinine is a measure of the mass of muscle tissue in the body (Shaffer, 1908;Hodgson and Lewis, 1928;McClugage et al, 1931;Hoagland et al, 1945;Friedemann etal., 1948), although several worker's (Beard, 1932;Keys et al, 1950) have questioned this relationship. Miller and Blyth (1952) have used the excretion of creatinine in the prediction of lean body mass.…”

“…While the excretion of creatinine is almost independent of variations in food intake (Folin, 1905;McClugage et al, 1931;Albanese and Wangerin, 1944;Friedemann et al, 1948), the greater portion of the non-protein nitrogen excretion depends on the intake of nitrogen in the diet (Folin, 1905). Consequently no significance can be attached to changes in the rate of non-protein nitrogen excretion without firstly considering the changes in nitrogen intake.…”