This thesis investigates the problem of transferring human motion and appearance from video to video preserving motion features, body shape, and visual quality. In other words, given two input videos, we investigate how to synthesize a new video, where a target person from the first video is placed into a new context performing different motions from the second video. Possible application domains are on graphics animations and entertainment media that rely on synthetic characters and virtual environments to create visual content. We introduce two novel methods for transferring appearance and retargeting human motion from monocular videos, and by consequence, increase the creative possibilities of visual content. Differently from recent appearance transferring methods, our approaches take into account 3D shape, appearance, and motion constraints. Specifically, our first method is based on a hybrid image-based rendering technique that exhibits competitive visual retargeting quality compared to state-of-the-art neural rendering approaches, even without computationally intensive training. Then, inspired by the advantages of the first method, we designed an end-to-end learning-based transferring strategy. Taking advantages of both differentiable rendering and the 3D parametric model, our second data-driven method produces a fully 3D controllable human model, i.e., the user can control the human pose and rendering parameters. Experiments on different videos show that our methods preserve specific features of the motion that must be maintained (e.g., feet touching the floor, hands touching a particular object) while holding the best values for appearance in terms of Structural Similarity (SSIM), Learned Perceptual Image Patch Similarity (LPIPS), Mean Squared Error (MSE), and Fréchet Video Distance (FVD). We also provide to the community a new dataset composed of several annotated videos with motion constraints for retargeting applications and paired motion sequences from different characters to evaluate transferring approaches.